Characterizations of coal fly ash nanoparticles and induced in vitro toxicity in cell lines

被引：9

作者：

Sambandam, Bharathi ^{[1
]}

Palanisami, Eganathan ^{[2
]}

Abbugounder, Rajasekar ^{[1
]}

Prakhya, Balakrishnamurthy ^{[3
]}

Thiyagarajan, Devasena ^{[1
]}

机构：

[1] Anna Univ, Ctr Nanosci & Technol, Madras 600025, Tamil Nadu, India

[2] MS Swaminathan Res Fdn, Plant Tissue Culture & Bioprospecting Lab, Madras 600113, Tamil Nadu, India

[3] Int Inst Biotechnol & Toxicol IIBAT, Padappai 601301, India

来源：

JOURNAL OF NANOPARTICLE RESEARCH | 2014年 / 16卷 / 02期

关键词：

Coal fly ash; Coal fly ash nanoparticles; MTT assay; Cytotoxicity; Environmental and health effects; LUNG EPITHELIAL-CELLS; DNA-DAMAGE; ULTRAFINE PARTICLES; OXIDATIVE STRESS; COMBUSTION; SIZE; IRON; METALS; CYTOTOXICITY; MOBILIZATION;

D O I：

10.1007/s11051-013-2217-x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The present study illustrates the characterization and cytotoxicity studies of coal fly ash nanoparticles (CFA-NPs). The coal fly ash (CFA) collected from electrostatic precipitator of a coal-fired power plant and the average size of the CFA-NPs was found to be 9-50 nm. Imaging techniques showed predominantly homogenous spherical shaped nanoparticles. The X-ray diffraction analysis and energy dispersive X-ray (EDAX) analysis spectra reveal the elemental constituents of the CFA-NPs contain several toxic heavy metals. Cytotoxicity of CFA-NPs was determined by MTT assay. Cellular metabolism is inhibited in a dose dependent manner by CFA concentrations varying from 13 to 800 mu g mL(-1). After 48 h exposure, the Hep2, A549 and HepG2 cell lines prove more sensitive to CFA-NPs at varying levels which results in IC50 (50 % inhibitory concentration) cytotoxicity end point.

引用

页数：9

共 50 条

[1] Characterizations of coal fly ash nanoparticles and induced in vitro toxicity in cell lines
Bharathi Sambandam
Eganathan Palanisami
Rajasekar Abbugounder
Balakrishnamurthy Prakhya
Devasena Thiyagarajan
Journal of Nanoparticle Research, 2014, 16
[2] Characterization of coal fly ash nanoparticles and their induced in vitro cellular toxicity and oxidative DNA damage in different cell lines
Sambandam, Bharathi
Devasena, Thiyagarajan
Islam, Villianur Ibrahim Hairul
Prakhya, Balkrishna Murthy
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 2015, 53 (09) : 585 - 593
[3] Comparative Toxicity of Fly Ash: An In Vitro Study
Rozhina, Elvira
Ishmukhametov, Ilnur
Nigamatzyanova, Laysan
Akhatova, Farida
Batasheva, Svetlana
Taskaev, Sergey
Montes, Carlos
Lvov, Yuri
Fakhrullin, Rawil
MOLECULES, 2021, 26 (07):
[4] In vitro cytotoxic and hemolytic potential of coal fly ash
Kaw, J.L.
Khanna, A.K.
Waseem, M.
Journal of Environmental Science and Health - Part A Environmental Science and Engineering, 1988, A23 (07): : 711 - 723
[5] Application of leaching tests for toxicity evaluation of coal fly ash
Tsiridis, V.
Samaras, P.
Kungolos, A.
Sakellaropoullos, G. P.
ENVIRONMENTAL TOXICOLOGY, 2006, 21 (04) : 409 - 416
[6] Impact of counterions on the toxicity of metallic nanoparticles on hepatic cell lines in vitro
Braeuning, Albert
Sieg, Holger
Boehmert, Linda
Lichtenstein, Dajana
Lampen, Alfonso
TOXICOLOGY LETTERS, 2017, 280 : S216 - S216
[7] Chloride Induced Reinforcement Corrosion in Mortars Containing Coal Bottom Ash and Coal Fly Ash
Menendez, Esperanza
Argiz, Cristina
Angel Sanjuan, Miguel
MATERIALS, 2019, 12 (12):
[8] Coal Fly Ash Induces Goblet Cell Hyperplasia
Borcherding, J.
Taft, P.
Chen, H.
Bagegni, M.
Grassian, V. H.
Comellas, A. P.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 187
[9] Toxicity Evaluation of Weathered Coal Fly Ash–Amended Manure Compost
S. S. S. Lau
J. W. C. Wong
Water, Air, and Soil Pollution, 2001, 128 : 243 - 254
[10] Comparative Study Of The Variability In The Compositions And The Effect Of Milling Time On Coal Fly Ash And Wood Fly Ash Nanoparticles
Ikumapayi, Omolayo M.
Akinlabi, Esther T.
MATERIALS TODAY-PROCEEDINGS, 2019, 18 : 5556 - 5564

← 1 2 3 4 5 →