Regulatory T Cells Move in When Gliomas Say "I DO"

被引：12

作者：

Choi, Bryan D. ^{[1
]}

Fecci, Peter E. ^{[2
]}

Sampson, John H. ^{[1
]}

机构：

[1] Duke Univ, Preston Robert Tisch Brain Tumor Ctr, Duke Brain Tumor Immunotherapy Program, Div Neurosurg,Dept Surg,Med Ctr, Durham, NC 27710 USA

[2] Massachusetts Gen Hosp, Dept Neurosurg, Boston, MA 02114 USA

来源：

CLINICAL CANCER RESEARCH | 2012年 / 18卷 / 22期

关键词：

BRAIN-TUMORS; CTLA-4; BLOCKADE; COMPARTMENT; SURVIVAL; IMMUNITY;

D O I：

10.1158/1078-0432.CCR-12-2801

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Indoleamine 2,3-dioxygenase (IDO) is an enzyme with known immunosuppressive and tolerogenic effects in cancer. Mounting evidence has associated IDO expression with the induction of regulatory T cells (Treg) and malignant progression. IDO inhibition may therefore provide a promising therapeutic approach for glioblastoma, where the need for novel treatment is great. Clin Cancer Res; 18(22); 6086-8. (C)2012 AACR.

引用

页码：6086 / 6088

页数：3

共 50 条

[41] When I say ... healing
Sternszus, Robert
Regehr, Glenn
MEDICAL EDUCATION, 2018, 52 (02) : 148 - 149
[42] When I say ... validity
Cook, David A.
MEDICAL EDUCATION, 2014, 48 (10) : 948 - 949
[43] When I say ... understand
Kelly, Martina
Dornan, Tim
Ruparell, Tinu
MEDICAL EDUCATION, 2018, 52 (12) : 1223 - 1224
[44] When I say ... diversity
Chiavaroli, Neville
Blitz, Julia
Cleland, Jennifer
MEDICAL EDUCATION, 2020, 54 (10) : 876 - 877
[45] When I say ... profession
Trimble, Michael
MEDICAL EDUCATION, 2019, 53 (10) : 965 - 966
[46] When I say . . . gamification
McDougall, Allan
MEDICAL EDUCATION, 2018, 52 (05) : 469 - 470
[47] When I say ... entrustability
ten Cate, Olle
MEDICAL EDUCATION, 2020, 54 (02) : 103 - 104
[48] When I say ... capability
Neve, Hilary
Hanks, Sally
MEDICAL EDUCATION, 2016, 50 (06) : 610 - 611
[49] When I say ... reliability
Norman, Geoff
MEDICAL EDUCATION, 2014, 48 (10) : 946 - 947
[50] When I say ... microlearning
Thillainadesan, Janani
Le Couteur, David G.
Haq, Inam
Wilkinson, Tim J.
MEDICAL EDUCATION, 2022, 56 (08) : 791 - 792

← 1 2 3 4 5 →