Determination of the Mechanical Properties of Model Lipid Bilayers Using Atomic Force Microscopy Indentation

被引:9
|
作者
Drabik, Dominik [1 ]
Gavutis, Martynas [2 ]
Valiokas, Ramunas [2 ]
Ulcinas, Arturas [2 ]
机构
[1] Univ Wroclaw, Fac Biotechnol, Lab Cytobiochem, PL-50383 Wroclaw, Poland
[2] Ctr Phys Sci & Technol, Dept Nanoengn, LT-02300 Vilnius, Lithuania
关键词
Lipid bilayers - Deformation;
D O I
10.1021/acs.langmuir.0c02181
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
By conducting a systematic study of model lipid membranes using the atomic force microscopy (AFM) indentation, we demonstrate the importance of an experimental protocol on the determination of their mechanical parameters. We refine the experimental approach by analyzing the influence of the contact mechanics models used to process the data, substrate preparation, and indenter geometry. We show that both bending rigidity and area compressibility can be determined from a single AFM indentation measurement.
引用
收藏
页码:13251 / 13262
页数:12
相关论文
共 50 条
  • [41] Mechanical properties of bovine articular cartilage under microscale indentation loading from atomic force microscopy
    Park, S.
    Costa, K. D.
    Ateshian, G. A.
    Hong, K-S
    PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, 2009, 223 (H3) : 339 - 347
  • [42] Measuring the Mechanical Properties of Living Cells Using Atomic Force Microscopy
    Thomas, Gawain
    Burnham, Nancy A.
    Camesano, Terri Anne
    Wen, Qi
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2013, (76):
  • [43] Mechanical properties of individual microtubules measured using atomic force microscopy
    Thomson, NH
    Kis, A
    Kasas, S
    Dietler, G
    Kulik, AJ
    Forró, L
    ELECTRONIC PROPERTIES OF NOVEL MATERIALS-MOLECULAR NANOSTRUCTURES, 2000, 544 : 482 - 486
  • [44] Probabilistic Estimation of Mechanical Properties of Biomaterials Using Atomic Force Microscopy
    Roy, Rajarshi
    Chen, Wenjin
    Cong, Lei
    Goodell, Lauri A.
    Foran, David J.
    Desai, Jaydev P.
    IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2014, 61 (02) : 547 - 556
  • [45] Sensing and Modelling Mechanical Response in Large Deformation Indentation of Adherent Cell Using Atomic Force Microscopy
    Shen, Tianyao
    Shirinzadeh, Bijan
    Zhong, Yongmin
    Smith, Julian
    Pinskier, Joshua
    Ghafarian, Mohammadali
    SENSORS, 2020, 20 (06)
  • [46] Indentation topometry in glasses by atomic force microscopy
    Moysan, C
    Rouxel, T
    Sangleboeuf, JC
    GLASS SCIENCE AND TECHNOLOGY, 2004, 77 : 301 - 306
  • [47] Indentation topometry in glasses by atomic force microscopy
    Rouxel, T
    Sangleboeuf, JC
    Moysan, C
    Truffin, B
    JOURNAL OF NON-CRYSTALLINE SOLIDS, 2004, 344 (1-2) : 26 - 36
  • [48] Determination of Crack Resistance of the Cover and Slide Glass by Indentation Method with the Visualization Using Atomic Force Microscopy
    Lapitskaya, V. A.
    Kuznetsova, T. A.
    Chizhik, S. A.
    DEVICES AND METHODS OF MEASUREMENTS, 2024, 15 (01): : 60 - 67
  • [49] An atomic force microscopy tip model for investigating the mechanical properties of materials at the nanoscale
    Alderighi, Michele
    Ierardi, Vincenzo
    Allegrini, Maria
    Fuso, Francesco
    Solaro, Roberto
    JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2008, 8 (05) : 2479 - 2482
  • [50] Relating elastic modulus to indentation response using atomic force microscopy
    Vanlandingham, MR
    McKnight, SH
    Palmese, GR
    Eduljee, RF
    Gillespie, JW
    McCulough, RL
    JOURNAL OF MATERIALS SCIENCE LETTERS, 1997, 16 (02) : 117 - 119