Recent progress of antibacterial natural products: Future antibiotics candidates

被引：56

作者：

Dai, Jiangkun ^{[1
,2
,3
]}

Han, Rui ^{[4
]}

Xu, Yujie ^{[4
]}

Li, Na ^{[5
]}

Wang, Junru ^{[1
,4
]}

Dan, Wenjia ^{[3
,4
]}

机构：

[1] Northwest A&F Univ, Coll Vet Med, Xian, Shaanxi, Peoples R China

[2] Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Taipa, Macao, Peoples R China

[3] Weifang Med Univ, Sch Life Sci & Technol, Weifang, Shandong, Peoples R China

[4] Northwest A&F Univ, Coll Chem & Pharm, Xian, Shaanxi, Peoples R China

[5] Northwest Univ, Coll Food Sci & Technol, Xian, Peoples R China

来源：

BIOORGANIC CHEMISTRY | 2020年 / 101卷

基金：

中国国家自然科学基金;

关键词：

Natural Products; Antibacterial; Drug Candidates; RESISTANT STAPHYLOCOCCUS-AUREUS; MONOTERPENOID INDOLE ALKALOIDS; ENDOPHYTIC FUNGUS; ANTIMICROBIAL ACTIVITY; STRUCTURE ELUCIDATION; ACID-DERIVATIVES; A-C; CYCLIC HEXAPEPTIDE; DIPHENYL ETHERS; METABOLITES;

D O I：

10.1016/j.bioorg.2020.103922

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The discovery of novel antibacterial molecules plays a key role in solving the current antibiotic crisis issue. Natural products have long been an important source of drug discovery. Herein, we reviewed 256 natural products from 11 structural classes in the period of 2016-01/2020, which were selected by SciFinder with new compounds or new structures and MICs lower than 10 mu g/mL or 10 mu M as criterions. This review will provide some effective antibacterial lead compounds for medicinal chemists, which will promote the antibiotics research based on natural products to the next level.

引用

页数：25

共 50 条

[21] Progress in Recent Study of Anti-HBV Natural Products and Extracts
Li, Yantao
Huang, Jianwei
Xu, Ruian
Cui, Xiuling
MINI-REVIEWS IN ORGANIC CHEMISTRY, 2013, 10 (03) : 241 - 253
[22] Recent Progress in Plant-Derived Natural Products as Antibiotic Adjuvants
Guo Q.
Zhang C.
Peng K.
Cai J.
Shipin Kexue/Food Science, 2020, 41 (23): : 255 - 265
[23] Recent progress in total synthesis and development of natural products using carbohydrates
Tatsuta, Kuniaki
Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 1997, 55 (11): : 970 - 981
[24] Recent progress in the synthesis of limonoids and limonoid-like natural products
Fu, Shaomin
Liu, Bo
ORGANIC CHEMISTRY FRONTIERS, 2020, 7 (14) : 1903 - 1947
[25] Recent progress toward the total synthesis of the arcutine family of natural products
Owens, Kyle
Hirooka, Yasuo
Ueno, Sohei
Sarpong, Richmond
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
[26] Antimicrobial Strategies based on Natural Products: Recent Progress in Bio and Nanotechnology
Holban, Alina M.
Grumezescu, Alexandru Mihai
CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 2015, 16 (02) : 85 - 86
[27] Natural products as Nrf2 modulators for ferroptosis inhibition in renal disease therapy: Recent progress and future prospects
Tian, Ruimin
Guo, Shan
Chen, Shudong
Wu, Jiaqi
Long, Aoyang
Cheng, Ran
Wang, Xiaowan
Huang, Lihua
Li, Chuang
Mao, Wei
Xu, Peng
Yu, Lili
Pan, Hudan
Liu, Liang
PHYTOMEDICINE, 2025, 136
[28] ANTIBIOTICS 1971 - SURVEY OF RECENT PROGRESS
PLOTKIN, SA
CLINICAL PEDIATRICS, 1971, 10 (07) : 369 - &
[29] Recent progress in the field of macrolide antibiotics
Henninger, TC
EXPERT OPINION ON THERAPEUTIC PATENTS, 2003, 13 (06) : 787 - 805
[30] Recent progress in the chemical synthesis of antibiotics
Boger, Dale L.
Journal of the American Chemical Society, 1992, 114 (03)

← 1 2 3 4 5 →