Immunocytochemical localization of the high-affinity glutamate transporter, EAACl, in the retina of representative vertebrate species

被引：39
|
作者：
Schulz, K
Stell, WK
机构：
[1] UNIV CALGARY,FAC MED,LIONS SIGHT CTR,CALGARY,AB T2N 4N1,CANADA
[2] UNIV CALGARY,FAC MED,NEUROSCI RES GRP,CALGARY,AB T2N 4N1,CANADA
[3] UNIV CALGARY,FAC MED,DEPT ANAT,CALGARY,AB T2N 4N1,CANADA
[4] UNIV CALGARY,FAC MED,DEPT SURG OPHTHALMOL,CALGARY,AB T2N 4N1,CANADA
来源：
NEUROSCIENCE LETTERS | 1996年 / 211卷 / 03期
关键词：
glutamate transporter; EAAC1; retina; goldfish; salamander; turtle; chicken; rat; immunocytochemistry;
D O I：
10.1016/0304-3940(96)12762-2
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The glutamate transporter, EAAC1, was localized immunocytochemically in goldfish, salamander, turtle, chicken, and rat retinas, using affinity-purified oligopeptide antibodies. Immunoreactive (IR) EAAC1 was present in the inner plexiform layer of all species, and in cell bodies of bipolar, amacrine, and ganglion cells of most species, but absent from photoreceptors and Muller's glial cells. Western blots revealed an IR-EAAC1 band at 70 kDa. Staining was abolished by preabsorption with EAAC1 peptide.
引用
收藏
页码：191 / 194
页数：4
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