Lipase-mediated resolution of cis-1-amino-2-indanol, the key component of the HIV protease inhibitor indinavir

被引：13
|
作者：
Anilkumar, AT [1 ]
Goto, K [1 ]
Takahashi, T [1 ]
Ishizaki, K [1 ]
Kaga, H [1 ]
机构：
[1] Hokkaido Natl Ind Res Inst, Sapporo, Hokkaido 0628517, Japan
来源：
TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 13期
关键词：
D O I：
10.1016/S0957-4166(99)00260-8
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The efficient and direct resolution of cis-1-amino-2-indanol using Candida antarctica lipase B catalyzing the alcoholysis of its N,O-diacetyl derivative is reported. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：2501 / 2503
页数：3
相关论文
共 50 条
  • [1] Lipase-mediated resolution of the key intermediates for the HIV protease inhibitor Indinavir.
    Kaga, H
    Anilkumar, AT
    Hirosawa, K
    Takahashi, T
    Goto, K
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 219 : U217 - U217
  • [2] Practical synthesis of (1S,2R)-1-amino-2-indanol, a key component of an HIV protease inhibitor, indinavir
    Bull Chem Soc Jpn, 5 (1093-1100):
  • [3] A Practical Synthesis of (1S, 2R)-1-Amino-2-indanol, a Key Component of HIV Protease Inhibitor, Indinavir
    Synlett, (01):
  • [4] A practical synthesis of (1S,2R)-1-amino-2-indanol, a key component of HIV protease inhibitor, indinavir
    Kajiro, H
    Mitamura, S
    Mori, A
    Hiyama, T
    SYNLETT, 1998, (01) : 51 - +
  • [5] Strategies for Accessing cis-1-Amino-2-Indanol
    Mendas, Ines
    Gastaldi, Stephane
    Suppo, Jean-Simon
    MOLECULES, 2024, 29 (11):
  • [6] Enantioselective synthesis of cyclic amino alcohols:: cis-1-amino-2-indanol
    Kim, Eun Jin
    An, Kyung Mi
    Ko, Soo Y.
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2006, 27 (12) : 2019 - 2022
  • [7] Applications of cis-1-amino-2-indanol in asymmetric synthesis
    Senanayake, CH
    ALDRICHIMICA ACTA, 1998, 31 (01) : 3 - 15
  • [8] Continuous-Flow Kinetic Resolution of (±)-cis-1-Amino-2-indanol by Lipase-Catalyzed N-Acetylation
    Kim, Yoon-Jung
    Choi, Yong-Sung
    Yang, Sai
    Yang, Woo Ram
    Jeong, Jin-Hyun
    SYNLETT, 2015, 26 (14) : 1981 - 1984
  • [9] A practical synthesis of (1S,2R)-1-amimo-2-indanol, a key component of an HIV protease inhibitor, indinavir
    Kajiro, H
    Mitamura, S
    Mori, A
    Hiyama, T
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1999, 72 (05) : 1093 - 1100
  • [10] Chemoenzymatic synthesis of (1S,2R)-1-amino-2-indanol, a key intermediate of HIV protease inhibitor, indinavir
    Demir, AS
    Hamamci, H
    Doganel, F
    Ozgul, E
    JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2000, 9 (4-6) : 157 - 161
12345