Synthesis and biological activity of some novel isoxazoles derived from benzosuberones

被引：0
|
作者：
Rupavani, Bandapally [1 ]
Venkateswarlu, Peesapati [1 ]
机构：
[1] Palamuru Univ, Adarsh Degree & PG Coll, Dept Chem, Mahabubnagar 509001, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2019年 / 58卷 / 04期
关键词：
2,3-Dimethy1-6,7,8,9-tetrahydrobenzocyclohepten-5-one; isoxazoles; anticancer activity;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A class of novel isoxazoles 3a-h derived from 2, 3-dimethyl-6-arylidene-6,7,8,9-tetrahydro-5H- benzo[a]cyclohepten5-ones 2a-h have been reported and characterized by spectral analysis. The compounds have been assayed for their potential anticancer activity on human cancer cell lines. Compounds 3a, 3c show moderate anti cancer activity towards prostate cancer and 3a, 3c, 3f show mild activity towards breast cancer.
引用
收藏
页码：511 / 515
页数：5
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