Generation and optimization of a chimeric antigen receptor against human CD22: A new immunotherapeutic agent for adoptive immunotherapy

被引：0
|
作者：
Haso, Waleed [1 ]
Lee, Daniel [1 ]
Morgan, Richard [1 ]
Pastan, Ira [1 ]
Mackall, Crystal [1 ]
Orentas, Rimas J. [1 ]
机构：
[1] NIH, Bethesda, MD 20892 USA
来源：
CANCER RESEARCH | 2012年 / 72卷
关键词：
D O I：
10.1158/1538-7445.AM2012-3504
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3504
引用
收藏
页数：1
相关论文
共 50 条
  • [21] Successful treatment of relapsed acute B-cell lymphoblastic leukemia with CD20/CD22 bispecific chimeric antigen receptor T-cell therapy
    Liang, Zuyu
    Cui, Jiazhen
    Chang, Alex Hongsheng
    Yu, Jian
    Hu, Yongxian
    Huang, He
    REGENERATIVE THERAPY, 2020, 15 : 281 - 284
  • [22] 1 Study of CD19/CD22 Bispecific Chimeric Antigen Receptor (CAR) Therapy in Children and Young Adults with B Cell Acute Lymphoblastic Leukemia (ALL)
    Schultz, Liora M.
    Davis, Kara L.
    Baggott, Christina
    Chaudry, Christie
    Marcy, Anne Cunniffe
    Mavroukakis, Sharon
    Sahaf, Bita
    Kong, Katherine A.
    Muffly, Lori S.
    Kim, Stephen
    Meyer, Everett H.
    Fry, Terry J.
    Qin, Haiying
    Miklos, David B.
    Mackall, Crystal L.
    BLOOD, 2018, 132
  • [23] The "3rd generation" chimeric immune receptor engineered T cells: Can we improve adoptive immunotherapy strategies against glioblastoma?
    Sahin, Ayguen
    Maxfield, Steven
    Bullain, Szofia
    Sanchez, Carlos
    Baratta, Elisabeth
    Carter, Bob S.
    HUMAN GENE THERAPY, 2008, 19 (10) : 1140 - 1140
  • [24] Determination of the effect of target site density on the efficacy of CD22 chimeric antigen receptor t-cell therapy to treat acute lymphoblastic leukemia.
    Sang Nguyen
    Majzner, Robbie G.
    Chien, Christopher
    Qin, Haiying
    Fry, Terry
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [25] GENERATION OF A NEW CHIMERIC ANTIGEN RECEPTOR TO TARGET CD23 EXPRESSED ON CHRONIC LYMPHOCYTIC LEUKEMIA CELLS
    Attianese, Giordano G. M. P.
    Hoyos, V
    Savoldo, B.
    Marin, V
    Brandi, M.
    Biondi, A.
    Biagi, E.
    Dotti, G.
    HAEMATOLOGICA, 2008, 93 : S32 - S32
  • [26] Efficacy and safety of chimeric antigen receptor T-cell therapy targeting CD19/CD22 in refractory/relapsed transformed aggressive B-cell lymphoma
    Xu, Hao
    Lv, Qiuxia
    Huang, Liang
    Cao, Wenyue
    Wang, Jue
    Meng, Fankai
    Li, Chunrui
    Zheng, Miao
    Chen, Liting
    Mu, Ketao
    Cheng, Jiali
    Zhu, Li
    Zhou, Jianfeng
    Zhang, Yicheng
    Wang, Na
    Cao, Yang
    CYTOTHERAPY, 2023, 25 (02) : 185 - 191
  • [27] Intracerebral delivery of a third generation EGFRvIII-specific chimeric antigen receptor is efficacious against human glioma
    Choi, Bryan D.
    Suryadevara, Carter M.
    Gedeon, Patrick C.
    Herndon, James E., II
    Sanchez-Perez, Luis
    Bigner, Darell D.
    Sampson, John H.
    JOURNAL OF CLINICAL NEUROSCIENCE, 2014, 21 (01) : 189 - 190
  • [28] Efficacy and Safety of Chimeric Antigen Receptor T Cells Therapy Strategy That Dual Targeting CD19 and CD22 to Treat Relapsed/Refractory Acute Lymphoblastic Leukemia in Adults
    Tu, Sanfang
    Zhou, Lijuan
    Huang, Rui
    Zhou, Xuan
    Yang, Jilong
    Li, Meifang
    Jin, Bo
    Wang, Langqi
    Zhuo, Yaqi
    Chen, Huifang
    Chang, Lung-Ji
    Li, Yuhua
    BLOOD, 2023, 142
  • [29] Combining a CD20 Chimeric Antigen Receptor and an Inducible Caspase 9 Suicide Switch to Improve the Efficacy and Safety of T Cell Adoptive Immunotherapy for Lymphoma
    Budde, Lihua E.
    Berger, Carolina
    Lin, Yukang
    Wang, Jinjuan
    Lin, Xubin
    Frayo, Shani E.
    Brouns, Shaunda A.
    Spencer, David M.
    Till, Brian G.
    Jensen, Michael C.
    Riddell, Stanley R.
    Press, Oliver W.
    PLOS ONE, 2013, 8 (12):
  • [30] Prevention of immune escape from chimeric antigen receptor T cells by loss of antigen expression in BCD19+ acute lymphoblastic leukemia via a CD19 and CD22 receptor co-targeting approach
    Nicoletti, Simon
    HEMATOLOGIE, 2024, 30 (01): : 15 - 17
12345