ASSAY CALIBRATION TO REFINE PREDICTION OF OATP1B1/1B3 MEDIATED DRUG-DRUG INTERACTIONS (DDI) BASED ON IN VITRO UPTAKE TRANSPORT ASSAY DATA

被引：0
|
作者：
Kovacs, Peter [1 ]
Sane, Rucha [1 ]
Cheung, Kit Wun Kathy [1 ]
Kis, Emese [1 ]
Plise, Emile [1 ]
Gaborik, Zsuzsanna [1 ]
机构：
[1] SOLVO Biotechnol, Szeged, Hungary
来源：
DRUG METABOLISM AND PHARMACOKINETICS | 2020年 / 35卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P228
引用
收藏
页码：S91 / S91
页数：1
相关论文
共 50 条
  • [31] Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3
    Noe, Johannes
    Portmann, Renee
    Brun, Marie-Elise
    Funk, Christoph
    DRUG METABOLISM AND DISPOSITION, 2007, 35 (08) : 1308 - 1314
  • [32] In Silico and in Vitro Assessment of OATP1B1 Inhibition in Drug Discovery
    Danielson, Matthew L.
    Sawada, Geri A.
    Raub, Thomas J.
    Desai, Prashant V.
    MOLECULAR PHARMACEUTICS, 2018, 15 (08) : 3060 - 3068
  • [33] Importance of OATP1B1 and 1B3 in the Liver Uptake of Luteolin and Its Consequent Glucuronidation Metabolites
    Zhi, Hui
    Yuan, Yuan
    Zhang, Chunzhen
    Jiang, Yiguo
    Zhang, Hongjian
    Wang, Cheng
    Ruan, Jianqing
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, 68 (07) : 2063 - 2070
  • [34] Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions
    Sharma, P.
    Holmes, V. E.
    Elsby, R.
    Lambert, C.
    Surry, D.
    XENOBIOTICA, 2010, 40 (01) : 24 - 37
  • [35] THE DRUG-DRUG INTERACTIONS OF CLOPIODGREL FOR OATP1B1 AND CYP2C8: IN VITRO PREDICTION AND A CLINICAL CASSETTE SMALL-DOSE STUDY
    Kim, Soo-Jin
    Yoshikado, Takashi
    Ieiri, Ichiro
    Kazuya, Maeda
    Kimura, Miyuki
    Irie, Shin
    Kusuhara, Hiroyuki
    Sugiyama, Yuichi
    DRUG METABOLISM AND PHARMACOKINETICS, 2017, 32 (01) : S53 - S53
  • [36] VARIABILITY OF OATP1B1/1B3 IN VITRO INHIBITION CONSTANTS AND THE RESULTING IMPACT ON CLINICAL EVALUATION
    McFeely, Savannah
    Ritchie, Tasha
    Ragueneau-Majlessi, Isabelle
    DRUG METABOLISM AND PHARMACOKINETICS, 2020, 35 (01) : S94 - S94
  • [37] Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1-and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1-and OATP1B3-Mediated Drug-Drug Interactions
    Farasyn, Taleah
    Crowe, Alexandra
    Hatley, Oliver
    Neuhoff, Sibylle
    Alam, Khondoker
    Kanyo, Jean
    Lam, TuKiet T.
    Ding, Kai
    Yue, Wei
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 108 (10) : 3443 - 3456
  • [38] Influence of the sulfonylurea drug glibenclamide on the OATP1B1-and OATP1B3-mediated uptake
    Klatt, S.
    Fromm, M. F.
    Koenig, J.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2011, 383 : 79 - 79
  • [39] In Vitro-ln Vivo Extrapolation of OATP1B-Mediated Drug-Drug Interactions in Cynomolgus Monkey
    Ufuk, Ayse
    Kosa, Rachel E.
    Gao, Hongying
    Bi, Yi-An
    Modi, Sweta
    Gates, Dana
    Rodrigues, A. David
    Tremaine, Larry M.
    Varma, Manthena V. S.
    Houston, J. Brian
    Galetin, Aleksandra
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018, 365 (03): : 688 - 699
  • [40] Quantitative prediction of OATP1B-mediated drug-drug interactions using endogenous biomarker coproporphyrin I
    Takubo, Hiroaki
    Bessho, Koji
    Watari, Ryosuke
    Shigemi, Ryota
    XENOBIOTICA, 2022, 52 (04) : 397 - 404
12345