ASSAY CALIBRATION TO REFINE PREDICTION OF OATP1B1/1B3 MEDIATED DRUG-DRUG INTERACTIONS (DDI) BASED ON IN VITRO UPTAKE TRANSPORT ASSAY DATA

被引：0
|
作者：
Kovacs, Peter [1 ]
Sane, Rucha [1 ]
Cheung, Kit Wun Kathy [1 ]
Kis, Emese [1 ]
Plise, Emile [1 ]
Gaborik, Zsuzsanna [1 ]
机构：
[1] SOLVO Biotechnol, Szeged, Hungary
来源：
DRUG METABOLISM AND PHARMACOKINETICS | 2020年 / 35卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P228
引用
收藏
页码：S91 / S91
页数：1
相关论文
共 50 条
  • [21] Preclinical Mouse Models To Study Human OATP1B1-and OATP1B3-Mediated Drug-Drug Interactions in Vivo
    Durmus, Selvi
    Lozano-Mena, Gloria
    van Esch, Anita
    Wagenaar, Els
    van Tellingen, Olaf
    Schinkel, Alfred H.
    MOLECULAR PHARMACEUTICS, 2015, 12 (12) : 4259 - 4269
  • [22] OATP1B1 in vitro inhibition assay enrichment & QSAR modeling
    Danielson, Matthew
    DRUG METABOLISM REVIEWS, 2016, 48 : 107 - 107
  • [23] The application of An OATP1B1 inhibition assay within drug discovery: Use of in vitro and in silico approaches to aid drug design
    Soars, Matt G.
    Barton, Patrick
    Grime, Ken
    Riley, Robert J.
    DRUG METABOLISM REVIEWS, 2009, 41 : 178 - 178
  • [24] Structure of human drug transporters OATP1B1 and OATP1B3
    Anca-Denise Ciută
    Kamil Nosol
    Julia Kowal
    Somnath Mukherjee
    Ana S. Ramírez
    Bruno Stieger
    Anthony A. Kossiakoff
    Kaspar P. Locher
    Nature Communications, 14
  • [25] Structure of human drug transporters OATP1B1 and OATP1B3
    Ciuta, Anca-Denise
    Nosol, Kamil
    Kowal, Julia
    Mukherjee, Somnath
    Ramirez, Ana S.
    Stieger, Bruno
    Kossiakoff, Anthony A.
    Locher, Kaspar P.
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [26] Drug-drug interaction between pitavastatin and various drugs via OATP1B1
    Hirano, Masaru
    Maeda, Kazuya
    Shitara, Yoshihisa
    Sugiyama, Yuichi
    DRUG METABOLISM AND DISPOSITION, 2006, 34 (07) : 1229 - 1236
  • [27] In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug–Drug Interactions
    Maria Karlgren
    Gustav Ahlin
    Christel A. S. Bergström
    Richard Svensson
    Johan Palm
    Per Artursson
    Pharmaceutical Research, 2012, 29 : 411 - 426
  • [28] Contribution of organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 to hepatic uptake of nateglinide, and the prediction of drug-drug interactions via these transporters
    Takanohashi, Toshiyuki
    Kubo, Satoru
    Arisaka, Harumi
    Shinkai, Kenji
    Ubukata, Kazuyuki
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2012, 64 (02) : 199 - 206
  • [29] REDUCED PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL FOR REPAGLINIDE: IMPACT OF OATP1B1 GENOTYPE AND SOURCE OF IN VITRO DATA ON THE PREDICTION OF DRUG-DRUG INTERACTION RISK
    Gertz, Michael
    Saell, Carolina
    Houston, J. Brian
    Galetin, Aleksandra
    DRUG METABOLISM REVIEWS, 2014, 45 : 258 - 258
  • [30] Effect of clotrimazole on transport mediated by human OATP1B1 and OATP1B3
    Gui, Chunshan
    Thompson, Lucas
    Hagenbuch, Bruno
    HEPATOLOGY, 2006, 44 (04) : 379A - 379A
12345