Iron-Catalyzed Intramolecular Reductive Coupling of Unactivated Aldehydes and Arylalkenes with Isopropanol

被引：5

作者：

Zheng, Yan-Long ^{[1
,2
]}

Liu, Yan-Yao ^{[1
,2
]}

Xu, Xue-Tao ^{[3
]}

Zhang, Kun ^{[3
]}

Ye, Mengchun ^{[1
,2
,3
]}

机构：

[1] Nankai Univ, State Key Lab, Coll Chem, Tianjin 300071, Peoples R China

[2] Nankai Univ, Inst Elementoorgan Chem, Coll Chem, Tianjin 300071, Peoples R China

[3] Wuyi Univ, Sch Chem & Environm Engn, Jiangmen 529020, Peoples R China

来源：

ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 7卷 / 03期

基金：

中国国家自然科学基金;

关键词：

alcohol; aldehyde; alkene; iron catalysis; reductive coupling; TRANSFER HYDROGENATIVE COUPLINGS; OXIDATIVE CYCLIZATION; ALDOL CYCLIZATIONS; KETONES; ETA(2)-ALKENE; 1,3-DIENE; COMPLEX; ENONES;

D O I：

10.1002/ajoc.201700622

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

FeCl3-catalyzed intramolecular reductive coupling of unactivated aldehydes and arylalkenes with isopropanol as a terminal reductant under mild and easy-to-handle conditions has been developed. A series of five-, six-, seven- and eight-membered carbocyclic alcohols were synthesized in moderate to excellent yields with high regioselectivities.

引用

页码：554 / 557

页数：4

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