COMBINED INHIBITION OF TOP1 AND PARP: A NOVEL THERAPEUTIC STRATEGY FOR GBM WITH PTEN DEFICIENCY

被引:0
|
作者
Kim, Olga [1 ]
Butler, Madison [2 ]
Robey, Robert [2 ]
Chari, Raj [3 ]
Sergi, Zach [4 ]
Zhang, Meili [3 ]
Pang, Ying [4 ]
Yu, Guangyang [3 ]
Zhang, Wei [3 ]
Song, Hua [3 ]
Davis, Dionne [3 ]
Wang, Herui [4 ]
Merchant, Mythili [4 ]
Ranjan, Alice [4 ]
Gilbert, Mark [1 ]
Gottesman, Michael [3 ]
Pommier, Yves [5 ]
Wu, Jing [1 ]
机构
[1] NCI, NIH, Neurooncol Branch, Bethesda, MD USA
[2] NCI, NIH, Bethesda, MD USA
[3] NIH, Bethesda, MD USA
[4] NCI, NOB, Bethesda, MD USA
[5] NCI, Bethesda, MD USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
EXTH-63
引用
收藏
页码:223 / 223
页数:1
相关论文
共 50 条
  • [41] A Novel Therapeutic Strategy Against MYCN-Amplified Neuroblastoma by Chemical-Induced Copy Number Reduction Combined with PARP Inhibitors
    Takatori, Atsushi
    Yoda, Hiroyuki
    Watanabe, Takayoshi
    Shinozaki, Yoshinao
    Nagase, Hiroki
    PEDIATRIC BLOOD & CANCER, 2020, 67
  • [42] Targeting TRIBBLES1 (TRIB1) Pseudokinase in GBM: A New Therapeutic Strategy
    Singh, K.
    Fleming, J.
    Han, C.
    Cui, T.
    Johnson, B.
    McElroy, J.
    Bell, E. H.
    Robe, P.
    Haque, S. J.
    Chakravarti, A.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2020, 108 (03): : E512 - E512
  • [43] Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma
    Chila, Rosaria
    Basana, Alessandra
    Lupi, Monica
    Guffanti, Federica
    Gaudio, Eugenio
    Rinaldi, Andrea
    Cascione, Luciano
    Restelli, Valentina
    Tarantelli, Chiara
    Bertoni, Francesco
    Damia, Giovanna
    Carrassa, Laura
    ONCOTARGET, 2015, 6 (05) : 3394 - 3408
  • [44] JQ1, a Potential Therapeutic Molecule for Myeloid Leukemia with PTEN Deficiency
    Baltz, Nicholas J.
    Colorado, Natalia C.
    Yan, Yan
    Lensing, Shelly
    Robinson, Delli
    Cottler-Fox, Michele H.
    Farrar, Jason E.
    Emanuel, Peter Dean
    Liu, Y. Lucy
    BLOOD, 2016, 128 (22)
  • [45] Poly(ADP-ribose) Polyremase-1 (PARP-1) Inhibition: A Promising Therapeutic Strategy for ETS-Expressing Tumours
    Legrand, Arnaud J.
    Choul-li, Souhaila
    Villeret, Vincent
    Aumercier, Marc
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (17)
  • [46] Can Nimesulide Nanoparticles Be a Therapeutic Strategy for the Inhibition of the KRAS/PTEN Signaling Pathway in Pancreatic Cancer?
    Ferreira, Roseane Guimaraes
    Mosquera Narvaez, Luis Eduardo
    Monteiro Espindola, Kaio Murilo
    Rosario, Amanda Caroline R. S.
    Lima, Wenddy Graziela N.
    Monteiro, Marta Chagas
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [47] PARP-1 Inhibition as a Targeted Strategy to Treat Ewing's Sarcoma
    Brenner, J. Chad
    Feng, Felix Y.
    Han, Sumin
    Patel, Sonam
    Goyal, Siddharth V.
    Bou-Maroun, Laura M.
    Liu, Meilan
    Lonigro, Robert
    Prensner, John R.
    Tomlins, Scott A.
    Chinnaiyan, Arul M.
    CANCER RESEARCH, 2012, 72 (07) : 1608 - 1613
  • [48] mTOR inhibition as a novel gene therapeutic strategy for diabetic retinopathy
    Lee, Steven Hyun Seung
    Lee, Joo Yong
    Choi, Jun-Sub
    Kim, Hee Jong
    Kim, Jin
    Cha, Seho
    Lee, Kyoung Jin
    Woo, Ha-Na
    Park, Keerang
    Lee, Heuiran
    PLOS ONE, 2022, 17 (06):
  • [49] Beta-catenin inhibition as a novel therapeutic strategy for porphyria
    Balogun, Anu
    Cornuet, Pamela
    Nejak-Bowen, Kari
    FASEB JOURNAL, 2022, 36
  • [50] Glutamate carboxypeptidase II (NAALADase) inhibition as a novel therapeutic strategy
    Thomas, AG
    Wozniak, KM
    Tsukamoto, T
    Calvin, D
    Wu, Y
    Rojas, C
    Vornov, J
    Slusher, BS
    N-ACETYLASPARTATE: A UNIQUE NEURONAL MOLECULE IN THE CENTRAL NERVOUS SYSTEM, 2006, 576 : 327 - 337