Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats

被引：6
|
作者：
Burgos, R
Forcelledo, M
Wagner, H
Muller, A
Hancke, J
Wikman, G
Croxatto, H
机构：
[1] SWEDISH HERBAL INST,GOTHENBURG,SWEDEN
[2] PONTIFICIA UNIV CATOLICA CHILE,FAC CIENCIAS BIOL,UNIDAD REPROD & DESAROLLO,SANTIAGO,CHILE
[3] UNIV MUNICH,INST PHARMAZEUT BIOL,MUNICH,GERMANY
来源：
PHYTOMEDICINE | 1997年 / 4卷 / 02期
关键词：
Adhatoda vasica; abortive effect; vasicine; rats;
D O I：
10.1016/S0944-7113(97)80061-X
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The possible abortive effect of an extract of Adhatoda vasica leaf spissum, was studied in rats. The principal alkaloid detected in the extract was vasicine (0.85 +/- 0.03%). The extract (325 mg/kg/day) was administered with a gastric cannula to a group of 5 pregnant females between day 1 and 9 of pregnancy. In another experiment 9 pregnant females received in the water 0.25 and 2.5% of Adhatoda vasica between day 1 and 9 of pregnancy. It was concluded that the administration of Adhatoda vasica did not produce abortion in any of the treated groups.
引用
收藏
页码：145 / 149
页数：5
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