Discovery and preliminary characterization of novel tyrosine kinase inhibitors with to BTK

被引:0
|
作者
Namdev, Nivedita D. [1 ]
Cornell-Kennon, Susan [1 ]
Yu, Yi [1 ]
Hill, Jason [1 ]
Bull, Cathy [1 ]
Volak, Laurie [1 ]
Wang, Jianqiang [1 ]
Lowe, Deirdre [1 ]
Gu, Xuibin [1 ]
Koerner, Steffi [1 ]
Moussa, Magdi [1 ]
Vensel, David [1 ]
Liu, Yanbin [1 ]
Wu, Hui [1 ]
Chen, Chang-Rung [1 ]
Dransfield, Daniel T. [1 ]
Ashwell, Mark A. [1 ]
机构
[1] ArQule Inc, Woburn, MA USA
关键词
D O I
10.1158/1535-7163.TARG-13-B270
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
B270
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Discovery and Characterization of Novel Mutant FLT3 Kinase Inhibitors
    Weisberg, Ellen
    Choi, Hwan Geun
    Barrett, Rosemary
    Zhou, Wenjun
    Zhang, Jianming
    Ray, Arghya
    Nelson, Erik A.
    Jiang, Jingrui
    Moreno, Daisy
    Stone, Richard
    Galinsky, Ilene
    Fox, Edward
    Adamia, Sophia
    Kung, Andrew L.
    Gray, Nathanael S.
    Griffin, James D.
    MOLECULAR CANCER THERAPEUTICS, 2010, 9 (09) : 2468 - 2477
  • [22] XLA - Studies on the Btk tyrosine kinase
    Smaith, CIE
    Backesjo, CM
    Branden, LJ
    Islam, T
    Mattsson, PT
    Mohamed, AJ
    Nore, BF
    Vargas, L
    Vihinen, M
    MOLECULAR IMMUNOLOGY, 1998, 35 (11-12) : 669 - 670
  • [23] Discovery of novel inhibitors of tyrosine kinases.
    Webb, TR
    Lvovskiy, D
    Heinrich, MC
    Yee, JWH
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 221 : U40 - U40
  • [24] Discovery and development of covalent BTK inhibitors
    Chen, Wei
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [25] Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases
    Shi, Qing
    Tebben, Andrew
    Dyckman, Alaric J.
    Li, Hedy
    Liu, Chunjian
    Lin, James
    Spergel, Steve
    Burke, James R.
    McIntyre, Kim W.
    Olini, Gilbert C.
    Strnad, Joann
    Surti, Neha
    Muckelbauer, Jodi K.
    Chang, Chiehying
    An, Yongmi
    Cheng, Lin
    Ruan, Qian
    Leftheris, Katerina
    Carter, Percy H.
    Tino, Joseph
    De Lucca, George V.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (09) : 2206 - 2211
  • [26] Discovery and Preclinical Characterization of Novel Small Molecule TRK and ROS1 Tyrosine Kinase Inhibitors for the Treatment of Cancer and Inflammation
    Narayanan, Ramesh
    Yepuru, Muralimohan
    Coss, Christopher C.
    Wu, Zhongzhi
    Bauler, Matthew N.
    Barrett, Christina M.
    Mohler, Michael L.
    Wang, Yun
    Kim, Juhyun
    Snyder, Linda M.
    He, Yali
    Levy, Nelson
    Miller, Duane D.
    Dalton, James T.
    PLOS ONE, 2013, 8 (12):
  • [27] Discovery of pyrido[3,4-b]indol-1-one derivatives as novel non-covalent Bruton's tyrosine kinase (BTK) inhibitors
    Dou, Dou
    Sha, Wenjie
    Diao, Yanyan
    Su, Rongrong
    Qiao, Yunjin
    Yu, Zhixiao
    Zhao, Zhenjiang
    Li, Honglin
    Chen, Zhuo
    Xu, Yufang
    BIOORGANIC CHEMISTRY, 2022, 119
  • [28] Discovery of Pteridine-7(8H)-one Derivatives as Potent and Selective Inhibitors of Bruton's Tyrosine Kinase (BTK)
    Dou, Dou
    Diao, Yanyan
    Sha, Wenjie
    Su, Rongrong
    Tong, Linjiang
    Li, Wenjie
    Leng, Limin
    Xie, Lijuan
    Yu, Zhixiao
    Song, Haoming
    Shen, Zihao
    Zhu, Lili
    Zhao, Zhenjiang
    Xie, Hua
    Chen, Zhuo
    Li, Honglin
    Xu, Yufang
    JOURNAL OF MEDICINAL CHEMISTRY, 2022, 65 (03) : 2694 - 2709
  • [29] Mutations in the Bruton Tyrosine Kinase (BTK) Gene in Patients with Chronic Lymphocytic Leukemia (CLL) Receiving BTK Inhibitors (BTKis)
    Skarbnik, Alan P.
    Danilov, Alexey V.
    Hoffmann, Marc
    Awan, Farrukh T.
    Scarpa, Frank
    Davies, Caryn
    Oakland, Todd
    Kovach, Marina
    Lilyquist, Jenna
    Munugalavadla, Veerendra
    Yong, Alan S. M.
    Shetty, Vikram
    Allan, John N.
    Woyach, Jennifer A.
    BLOOD, 2024, 144 : 4623 - 4624
  • [30] Discovery of Tricyclic Pyranochromenone as Novel Bruton's Tyrosine Kinase Inhibitors with In Vivo Antirheumatic Activity
    Cho, Hyewon
    Lee, Eun
    Kwon, Hye Ah
    Seul, Lee
    Jeon, Hui-Jeon
    Yu, Ji Hoon
    Ryu, Jae-Ha
    Jeon, Raok
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (21) : 1 - 15