STEM CELLS Dual response to Ras mutation

被引:0
|
作者
Chu, S. Haihua [1 ]
Armstrong, Scott A. [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, New York, NY 10065 USA
关键词
MICE;
D O I
10.1038/nature12840
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Proliferation-driving mutations in haematopoietic stem cells often result in the loss of stem-cell properties. But at least one common oncogenic mutation seems to enhance both proliferation and stem-cell self-renewal. See Letter p.143
引用
收藏
页码:91 / 92
页数:2
相关论文
共 50 条
  • [41] Stress response in mesoangioblast stem cells
    Geraci, F.
    Turturici, G.
    Galli, D.
    Cossu, G.
    Giudice, G.
    Sconzo, G.
    CELL DEATH AND DIFFERENTIATION, 2006, 13 (07): : 1057 - 1063
  • [42] Stress response in mesoangioblast stem cells
    F Geraci
    G Turturici
    D Galli
    G Cossu
    G Giudice
    G Sconzo
    Cell Death & Differentiation, 2006, 13 : 1057 - 1063
  • [43] Ras activation contributes the maintenance and expansion of putative cancer stem cells in breast cancer cells
    Nam, Jeong-Seok
    Kim, Ran-Ju
    Kim, Soo-Rim
    Park, Sang-Bum
    Roh, Kyung-Jin
    Cho, Eun-Mi
    Kang, Kyung-Sun
    Tang, Binwu
    Yang, Yu-An
    Kohn, Ethan
    Wakefield, Lalage
    CANCER RESEARCH, 2009, 69
  • [44] DUAL RAS PATHWAYS IN MURINE NIH 3T3 CELLS
    SILBERMAN, S
    SCHULTZ, RM
    FASEB JOURNAL, 1994, 8 (05): : A667 - A667
  • [45] On Target to Dual Block RAS?
    Papadopoulos, Dimitris P.
    Papademetriou, Vasilios
    Makris, Thomas K.
    ANGIOLOGY, 2009, 60 (06) : 739 - 749
  • [46] The dual role of mesenchymal stem cells in tumor progression
    Freitas Gomes, Celia Maria
    STEM CELL RESEARCH & THERAPY, 2013, 4
  • [47] POINT MUTATION IN C-HA-RAS ONCOGENE IN NORMAL AND ABNORMAL-CELLS
    NAG, A
    JONES, JA
    SMITH, RG
    LANCET, 1989, 1 (8632): : 274 - 275
  • [48] The dual role of mesenchymal stem cells in tumor progression
    Célia Maria Freitas Gomes
    Stem Cell Research & Therapy, 4
  • [49] A dual role of Erk signaling in embryonic stem cells
    Ma, Xinwei
    Chen, Haixia
    Chen, Lingyi
    EXPERIMENTAL HEMATOLOGY, 2016, 44 (03) : 151 - 156
  • [50] The dual role of mesenchymal stem cells in apoptosis regulation
    Chen, Zhuo
    Xia, Xuewei
    Yao, Mengwei
    Yang, Yi
    Ao, Xiang
    Zhang, Zhaoqi
    Guo, Li
    Xu, Xiang
    CELL DEATH & DISEASE, 2024, 15 (04)