STEM CELLS Dual response to Ras mutation

被引：0

作者：

Chu, S. Haihua ^{[1
]}

Armstrong, Scott A. ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, New York, NY 10065 USA

来源：

NATURE | 2013年 / 504卷 / 7478期

关键词：

MICE;

D O I：

10.1038/nature12840

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Proliferation-driving mutations in haematopoietic stem cells often result in the loss of stem-cell properties. But at least one common oncogenic mutation seems to enhance both proliferation and stem-cell self-renewal. See Letter p.143

引用

页码：91 / 92

页数：2

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