HALENAQUINONE DERIVATIVES FROM TROPICAL MARINE SPONGE XESTOSPONGIA SP.

被引:6
|
作者
Lee, Yeon-Ju [1 ]
Kim, Chang-Kwon [1 ]
Park, Song-Kyu [2 ]
Kang, Jong Soon [3 ]
Lee, Jong Seok [1 ]
Shin, Hee Jae [1 ]
Lee, Hyi-Seung [1 ]
机构
[1] Korea Ocean Res & Dev Inst, Marine Nat Prod Lab, Ansan 426744, South Korea
[2] Korea Univ, Coll Pharm, Yeongi 339700, Chungnam, South Korea
[3] Korea Res Iinst Biosci & Biotechnol, Bioevaluat Ctr, Cheongwon 363883, Chungbuk, South Korea
关键词
Tropical Sponge; Xestospongia sp; Xestosaprol; Halenaquinone; Cell Growth Inhibition; PROTEIN-TYROSINE KINASE; PENTACYCLIC POLYKETIDE; INHIBITORS; IDENTIFICATION; XESTOQUINONE; SAPRA;
D O I
10.3987/COM-12-12424
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Chemical investigations of the tropical marine sponge of the genus Xestospongia have resulted in the isolation of a new halenaquinone derivative named xestosaprol N (8) together with known metabolites. Their structures were elucidated on the basis of mass spectrometry and detailed 2D NMR spectroscopic data.
引用
收藏
页码:895 / 901
页数:7
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