ULTRASOUND-MEDIATED SYNTHESIS OF 3,4-DIHYDROPYRIMIDIN-2-(1H)-ONES (OR THIONES) WITH NaHSO4•H2O

被引：16
|
作者：
Dilmaghani, Karim Akbari [1 ]
Zeynizadeh, Behzad [1 ]
Amirpoor, Maryam [1 ]
机构：
[1] Urmia Univ, Fac Sci, Dept Chem, Orumiyeh 57159165, Iran
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2013年 / 188卷 / 11期
关键词：
3; 4-Dihydropyrimidin-2-(1H)-ones; aldehydes; -dicarbonyls; NaHSO4 center dot H2O; ultrasound; ONE-POT SYNTHESIS; IMPROVED PROTOCOL CONDITIONS; SOLVENT-FREE; EFFICIENT SYNTHESIS; SULFUR DERIVATIVES; REUSABLE CATALYST; CONDENSATION REACTION; RECYCLABLE CATALYST; ASSISTED SYNTHESIS; BIGINELLI REACTION;
D O I：
10.1080/10426507.2013.777725
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A fast and efficient Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-ones (or thiones) by the reaction of aromatic aldehydes, -dicarbonyls, and urea/thiourea using NaHSO4H2O/ultrasound system is presented. The reactions were carried out in refluxing n-hexane/CH3CN (2.5:0.5mL) to afford the products in excellent yields.
引用
收藏
页码：1634 / 1642
页数：9
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