Isolated left ventricular arrhythmogenic cardiomyopathy: A case report

被引：4

作者：

Barbosa-Barros, Raimundo ^{[1
]}

Perez-Riera, Andres Ricardo ^{[2
]}

de Abreu, Luiz Carlos ^{[2
]}

de Sousa-Rocha, Ricardo Paulo ^{[1
]}

da Costa Lino, Danielli Oliveira ^{[1
]}

Baranchuk, Adrian ^{[3
]}

Zhang, Li ^{[4
,5
]}

机构：

[1] Hosp Messejana Dr Carlos Alberto Studart Gomes, Coronary Ctr, Fortaleza, Ceara, Brazil

[2] ABC Sch Med, Design Studies & Sci Writing Lab, Sao Paulo, Brazil

[3] Queens Univ, Div Cardiol, Kingston, ON, Canada

[4] Lankenau Med Ctr, Wynnewood, PA USA

[5] Lankenau Inst Med Res, Wynnewood, PA USA

来源：

JOURNAL OF ELECTROCARDIOLOGY | 2017年 / 50卷 / 01期

关键词：

Isolated left ventricular arrhythmogenic cardiomyopathy; Electrocardiogram; Intercalated disc;

D O I：

10.1016/j.jelectrocard.2016.09.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Left ventricular involvement in the advanced stage of arrhythmogenic cardiomyopathy (AC) is an evolution of this desmosomopathy. Mutation in intercalated discs explains the phenotypic variability. Abnormal trafficking of the intercalated discs at the site of end-to-end contacts between cardiomyocytes and the canonical Wnt/beta-catenin and Hippo signaling pathways have been implicated. In AC, T-wave inversion in lateral leads is the hallmark of left ventricular (LV) involvement. We herein report a case of isolated LV AC in which the initial ECG has typical features: fragmented QRS (fQRS), Twave inversion (TWI) in lateral leads, and ventricular tachycardia from inferobasal LV wall. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：144 / 147

页数：4

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