Synthesis of new functionalized derivatives of 1,2,4-triazolo[4′,3′:2,3][1,2,4]triazino[5,6-b]indole

被引：12
|
作者：
Gomha, Sobhi M. [1 ]
Abdel-Aziz, Hatem A. [2 ]
机构：
[1] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt
[2] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia
来源：
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY | 2013年 / 78卷 / 08期
关键词：
hydrazonoyl halides; 1,2,4-triazino[5,6-b]indole-3-thione; hydrazonothioates; CHEMOTHERAPEUTIC-AGENTS; INHIBITION; MECHANISM;
D O I：
10.2298/JSC120914013G
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
New functionalized 1,2,4-triazolo[4',3':2,3][1,2,4]triazino[5,6-b]indole derivatives were synthesized via reaction of the hydrazonoyl halides with 2,4-dihydro-3H-1,2,4-triazino[5,6-b]indole-3-thione or its 3-methylthio derivative. The mechanism and the regioselectivity of the studied reactions are discussed.
引用
收藏
页码：1119 / 1125
页数：7
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