Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1′,2′-5,6]pyrano[3,4-d](1,2,3)selenadiazole and its derivatives

被引：49
|
作者：
Karnik, A. V. [1 ]
Kulkarni, A. M. [1 ]
Malviya, N. J. [1 ]
Mourya, B. R. [2 ]
Jadhav, B. L. [2 ]
机构：
[1] Univ Bombay, Dept Chem, Bombay 400098, Maharashtra, India
[2] Univ Bombay, Dept Life Sci, Bombay 400098, Maharashtra, India
来源：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2008年 / 43卷 / 11期
关键词：
Anti-bacterial activity; Semicarbazones; Annulation; 1,2,3-Selenadiazole; Naphthopyran;
D O I：
10.1016/j.ejmech.2008.01.026
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Synthesis of new heterocyclic compounds 3a-e containing naphthopyran and selenadiazole as the heterocyclic sub-units in the molecule is achieved using high yielding synthetic protocol. These molecules 3a-e have shown moderate anti-bacterial activity against some gram-positive and grain-negative bacterias. (C) 2008 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：2615 / 2617
页数：3
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