Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1′,2′-5,6]pyrano[3,4-d](1,2,3)selenadiazole and its derivatives

被引：49

作者：

Karnik, A. V. ^{[1
]}

Kulkarni, A. M. ^{[1
]}

Malviya, N. J. ^{[1
]}

Mourya, B. R. ^{[2
]}

Jadhav, B. L. ^{[2
]}

机构：

[1] Univ Bombay, Dept Chem, Bombay 400098, Maharashtra, India

[2] Univ Bombay, Dept Life Sci, Bombay 400098, Maharashtra, India

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2008年 / 43卷 / 11期

关键词：

Anti-bacterial activity; Semicarbazones; Annulation; 1,2,3-Selenadiazole; Naphthopyran;

D O I：

10.1016/j.ejmech.2008.01.026

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Synthesis of new heterocyclic compounds 3a-e containing naphthopyran and selenadiazole as the heterocyclic sub-units in the molecule is achieved using high yielding synthetic protocol. These molecules 3a-e have shown moderate anti-bacterial activity against some gram-positive and grain-negative bacterias. (C) 2008 Elsevier Masson SAS. All rights reserved.

引用

页码：2615 / 2617

页数：3

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