Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in ovarian cancer

被引:0
|
作者
Timms, Kirsten M. [1 ]
Abkevich, Victor [1 ]
Hennessy, Bryan T. [2 ]
Potter, Jennifer [1 ]
Carey, Mark S. [3 ]
Meyer, Larissa A. [4 ]
Broaddus, Russell [4 ]
Lu, Karen H. [4 ]
Jammulapati, Srikanth [1 ]
FitzGerald, Lisa [1 ]
Krivak, Thomas C. [5 ]
DeLoia, Julie A. [6 ]
Gutin, Alexander [1 ]
Mills, Gordon B. [4 ]
Lanchbury, Jerry [1 ]
机构
[1] Myriad Genet Inc, Salt Lake City, UT USA
[2] Beaumont Hosp, Dublin 9, Ireland
[3] Univ British Columbia, Vancouver, BC V5Z 1M9, Canada
[4] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[5] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA
[6] George Washington Univ, Washington, DC USA
关键词
D O I
10.1158/1538-7445.AM2012-3116
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3116
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Homologous recombination proficiency in ovarian and breast cancer patients
    Creeden, Justin Fortune
    Nanavaty, Nisha S.
    Einloth, Katelyn R.
    Gillman, Cassidy E.
    Stanbery, Laura
    Hamouda, Danae M.
    Dworkin, Lance
    Nemunaitis, John
    BMC CANCER, 2021, 21 (01)
  • [42] Different Patterns of Platinum Resistance in Ovarian Cancer Cells with Homologous Recombination Proficient and Deficient Background
    Chiappa, Michela
    Guffanti, Federica
    Grasselli, Chiara
    Panini, Nicolo
    Corbelli, Alessandro
    Fiordaliso, Fabio
    Damia, Giovanna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (05)
  • [43] Defects in homologous recombination repair behind the human diseases: FA and HBOC
    Katsuki, Yoko
    Takata, Minoru
    ENDOCRINE-RELATED CANCER, 2016, 23 (10) : T19 - T37
  • [44] Bi-allelic alterations in DNA repair genes underpin homologous recombination DNA repair defects in breast cancer
    Mutter, Robert W.
    Riaz, Nadeem
    Ng, Charlotte K. Y.
    Delsite, Rob
    Piscuoglio, Salvatore
    Edelweiss, Marcia
    Martelotto, Luciano G.
    Sakr, Rita A.
    King, Tari A.
    Giri, Dilip D.
    Drobnjak, Maria
    Brogi, Edi
    Bindra, Ranjit
    Bernheim, Giana
    Lim, Raymond S.
    Blecua, Pedro
    Desrichard, Alexis
    Higginson, Dan
    Towers, Russell
    Jiang, Ruomu
    Lee, William
    Weigelt, Britta
    Reis-Filho, Jorge S.
    Powell, Simon N.
    JOURNAL OF PATHOLOGY, 2017, 242 (02): : 165 - 177
  • [45] Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors
    Wang, Junhui
    Ding, Qianshan
    Fujimori, Hiroaki
    Motegi, Akira
    Miki, Yoshio
    Masutani, Mitsuko
    ONCOTARGET, 2016, 7 (07) : 7701 - 7713
  • [46] Aggressive prostate cancer with somatic loss of the homologous recombination repair gene FANCA: a case report
    Hongo, Hiroshi
    Kosaka, Takeo
    Aimono, Eriko
    Nishihara, Hiroshi
    Oya, Mototsugu
    DIAGNOSTIC PATHOLOGY, 2020, 15 (01)
  • [47] Aggressive prostate cancer with somatic loss of the homologous recombination repair gene FANCA: a case report
    Hiroshi Hongo
    Takeo Kosaka
    Eriko Aimono
    Hiroshi Nishihara
    Mototsugu Oya
    Diagnostic Pathology, 15
  • [48] Homologous Recombination Repair Mechanisms in Serous Endometrial Cancer
    Jonsson, Jenny-Maria
    Baath, Maria
    Bjornheden, Ida
    Sahin, Irem Durmaz
    Masback, Anna
    Hedenfalk, Ingrid
    CANCERS, 2021, 13 (02) : 1 - 15
  • [49] Characteristics of homologous recombination repair pathway genes mutation in ovarian cancers
    Yi, Zongbi
    Chen, Min
    Sun, Shaoxing
    Yang, Chunxu
    Mei, Zijie
    Yang, Hui
    Xiang, Qingming
    Qiu, Hui
    CANCER INNOVATION, 2022, 1 (03): : 220 - 228
  • [50] Evaluation of BRCA1/2 and homologous recombination defects in ovarian cancer and impact on clinical outcomes
    Yates, Melinda S.
    Timms, Kirsten
    Daniels, Molly S.
    Oakley, Holly D.
    Munsell, Mark F.
    Lanchbury, Jerry S.
    Lu, Karen H.
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35