Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in ovarian cancer

被引:0
|
作者
Timms, Kirsten M. [1 ]
Abkevich, Victor [1 ]
Hennessy, Bryan T. [2 ]
Potter, Jennifer [1 ]
Carey, Mark S. [3 ]
Meyer, Larissa A. [4 ]
Broaddus, Russell [4 ]
Lu, Karen H. [4 ]
Jammulapati, Srikanth [1 ]
FitzGerald, Lisa [1 ]
Krivak, Thomas C. [5 ]
DeLoia, Julie A. [6 ]
Gutin, Alexander [1 ]
Mills, Gordon B. [4 ]
Lanchbury, Jerry [1 ]
机构
[1] Myriad Genet Inc, Salt Lake City, UT USA
[2] Beaumont Hosp, Dublin 9, Ireland
[3] Univ British Columbia, Vancouver, BC V5Z 1M9, Canada
[4] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[5] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA
[6] George Washington Univ, Washington, DC USA
关键词
D O I
10.1158/1538-7445.AM2012-3116
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3116
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Exploiting defects in homologous recombination repair for metastatic, castration-resistant prostate cancer
    Chau, Vincent
    Madan, Ravi A.
    Figg, William D.
    CANCER BIOLOGY & THERAPY, 2020, 21 (10) : 884 - 887
  • [22] The role of KMT2C in the homologous recombination repair in epithelial ovarian cancer
    Ma, Mirielle C.
    Lin, Z. Ping
    Ratner, Elena S.
    CANCER RESEARCH, 2024, 84 (06)
  • [23] Prevalence and outcomes of germline pathogenic variants of homologous recombination repair genes in ovarian cancer
    Miwa, Maiko
    Kitagawa, Masakazu
    Asami, Yuka
    Kobayashi-Kato, Mayumi
    Watanabe, Takafumi
    Ogasawara, Aiko
    Hiranuma, Kengo
    Kato, Hisamori
    Saito, Motonobu
    Miyagi, Yohei
    Kato, Tomoyasu
    Yoshida, Hiroshi
    Momozawa, Yukihide
    Kohno, Takashi
    Shiraishi, Kouya
    Hasegawa, Kosei
    CANCER SCIENCE, 2024, 115 (12) : 3952 - 3962
  • [24] Homologous recombination deficiency in epithelial ovarian cancer
    Bartl, Thomas
    Paspalj, Valentina
    Grimm, Christoph
    MEMO-MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY, 2020, 13 (04) : 367 - 370
  • [25] Homologous recombination deficiency in epithelial ovarian cancer
    Thomas Bartl
    Valentina Paspalj
    Christoph Grimm
    memo - Magazine of European Medical Oncology, 2020, 13 : 367 - 370
  • [26] Evaluation of Homologous Recombination Deficiency in Ovarian Cancer
    Rubina Ratnaparkhi
    Melissa Javellana
    Andrea Jewell
    Lori Spoozak
    Current Treatment Options in Oncology, 2024, 25 : 237 - 260
  • [27] Evaluation of Homologous Recombination Deficiency in Ovarian Cancer
    Ratnaparkhi, Rubina
    Javellana, Melissa
    Jewell, Andrea
    Spoozak, Lori
    CURRENT TREATMENT OPTIONS IN ONCOLOGY, 2024, 25 (02) : 237 - 260
  • [28] Assessment of Homologous Recombination Deficiency in Ovarian Cancer
    Garg, Vikas
    Oza, Amit M.
    CLINICAL CANCER RESEARCH, 2023, 29 (16) : 2957 - 2960
  • [29] Extensive loss of heterozygosity is suppressed during homologous repair of chromosomal breaks
    Stark, JM
    Jasin, M
    MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (02) : 733 - 743
  • [30] TP53 mutations, tetraploidy and homologous recombination repair defects in early stage high-grade serous ovarian cancer
    Chien, Jeremy
    Sicotte, Hugues
    Fan, Jian-Bing
    Humphray, Sean
    Cunningham, Julie M.
    Kalli, Kimberly R.
    Oberg, Ann L.
    Hart, Steven N.
    Li, Ying
    Davila, Jaime I.
    Baheti, Saurabh
    Wang, Chen
    Dietmann, Sabine
    Atkinson, Elizabeth J.
    Asmann, Yan W.
    Bell, Debra A.
    Ota, Takayo
    Tarabishy, Yaman
    Kuang, Rui
    Bibikova, Marina
    Cheetham, R. Keira
    Grocock, Russell J.
    Swisher, Elizabeth M.
    Peden, John
    Bentley, David
    Kocher, Jean-Pierre A.
    Kaufmann, Scott H.
    Hartmann, Lynn C.
    Shridhar, Viji
    Goode, Ellen L.
    NUCLEIC ACIDS RESEARCH, 2015, 43 (14) : 6945 - 6958