Three new polyketides from Ascotricha sp. ZJ-M-5 by the OSMAC strategy

被引：3

作者：

Dong, Ya-Jing ^{[1
,2
]}

Hou, Guo-Mei ^{[1
,2
]}

Lin, Bin ^{[3
]}

Li, Dan-Yi ^{[2
]}

Li, Zhan-Lin ^{[1
,2
]}

机构：

[1] Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China

[2] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang 110016, Liaoning, Peoples R China

[3] Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang 110016, Liaoning, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2019年 / 21卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Ascotricha; OSMAC; polyketide; isocoumarin; ascotrichol; ascotrichrone A; STRUCTURE ELUCIDATION; FUNGUS;

D O I：

10.1080/10286020.2018.1471066

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new compounds, ascotrichols A-B (1-2) and ascotrichrone A (3), along with two known isocoumarin derivatives (4-5), were isolated from the solid culture of a sea mud-derived fungus, Ascotricha sp. ZJ-M-5 on rice media. The structures were elucidated by extensive spectroscopic analyses, including 1D and 2D NMR data, and the absolute configurations were determined by electronic circular dichroism and biogenetic correlation. [GRAPHICS] .

引用

页码：689 / 695

页数：7

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