In clinical research, computing sample size is important. A cross-over design (CD) is widely used for comparing treatment groups such as active treatment and control groups. In the analysis of multi-omits data such as metabolomics data, we often adopt the CD to identify biomarkers that have treatment effects. In this study, we propose a new method to compute the sample size of CDs with multiple treatment groups.
机构:
Queen Mary Univ London, Sch Math Sci, London E1 4NS, England
Univ St Andrews, Sch Math & Stat, St Andrews KY16 9SS, Fife, ScotlandQueen Mary Univ London, Sch Math Sci, London E1 4NS, England
Bailey, R. A.
Druilhet, P.
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机构:
ClermonT Univ, UMR CNRS 6620, Math Lab, F-63177 Aubiere, France
Univ Clermont Ferrand, F-63177 Aubiere, FranceQueen Mary Univ London, Sch Math Sci, London E1 4NS, England
Druilhet, P.
ANNALS OF STATISTICS,
2014,
42
(06):
: 2282
-
2300
机构:
Temple Univ, Fox Business Sch Management, Dept Stat, Philadelphia, PA 19122 USATemple Univ, Fox Business Sch Management, Dept Stat, Philadelphia, PA 19122 USA
Raghavarao, D
Yang, X
论文数: 0引用数: 0
h-index: 0
机构:
Temple Univ, Fox Business Sch Management, Dept Stat, Philadelphia, PA 19122 USATemple Univ, Fox Business Sch Management, Dept Stat, Philadelphia, PA 19122 USA