Design, synthesis, and preclinical evaluation of 7-benzyl -N-substituted phenyl-5H-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with antitubulin and antiangiogenic activity as antitumor agents

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作者
Gangjee, Aleem [1 ]
Pavana, Roheeth Kumar [1 ]
Ihnat, Michael A. [2 ]
Hamel, Ernest [3 ]
机构
[1] Duquesne Univ, Grad Sch Pharmaceut Sci, Div Med Chem, Pittsburgh, PA 15282 USA
[2] Univ Oklahoma, Hlth Sci Ctr, Coll Pharm, Dept Pharmaceut Sci, Oklahoma City, OK 73117 USA
[3] NCI, Screening Technol Branch, Dev Therapeut Program, Div Canc Treatment & Diag,Frederick Natl Lab Canc, Frederick, MD 21702 USA
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O6 [化学];
学科分类号
0703 ;
摘要
321-MEDI
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页数:1
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