Three-Component One-Pot Synthesis of 4-Aryl-2,3-dihydropyrimido[1,2-a]benzimidazol-2-ones Catalyzed by l-Proline

被引:6
|
作者
Sheibani, Hassan [1 ]
Saidi, Kazem [1 ]
Lakaei, Molod [1 ]
机构
[1] Shahid Bahonar Univ Kerman, Dept Chem, Kerman 76169, Iran
关键词
D O I
10.1002/jhet.1030
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient chemoselective synthesis of 4-aryl-2,3-dihydropyrimido[1,2-a]benzimidazol-2-one derivatives from three-component reactions of 2-aminobenzimidazole, Meldrum's acid, and aldehydes via [3+3] atom combination is described. The reaction occurs in different conditions such as in DMF as solvent at reflux and in the presence of l-proline as base catalyst.
引用
收藏
页码:1386 / 1390
页数:5
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