Azithromycin Alleviates Cigarette Smoke Induced Epithelial Mesenchymal Transition (EMT), Airway Inflammation and Enhances Antioxidant Mechanisms in COPD

被引:0
|
作者
Jain, S. [1 ]
Durugkar, S. [1 ]
Saha, P. [1 ]
Eapen, M. S. [2 ]
Sharma, P. [3 ]
Naidu, V. [1 ]
Sohal, S. S. [2 ]
机构
[1] NIPER, Pharmcol, Gauhati, India
[2] Univ Tasmania, Resp Translat Res Grp, Launceston, Tas, Australia
[3] Thomas Jefferson Univ, Dept Med, Philadelphia, PA 19107 USA
关键词
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A4071
引用
收藏
页数:2
相关论文
共 50 条
  • [42] Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke
    Yang, De-Qing
    Zuo, Qiu-Nan
    Wang, Tao
    Xu, Dan
    Lian, Liu
    Gao, Li-Juan
    Wan, Chun
    Chen, Lei
    Wen, Fu-Qiang
    Shen, Yong-Chun
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021, 2021
  • [43] MTOR Suppresses Cigarette Smoke-Induced Epithelial Cell Death and Airway Inflammation in Chronic Obstructive Pulmonary Disease
    Wang, Yong
    Liu, Juan
    Zhou, Jie-Sen
    Huang, Hua-Qiong
    Li, Zhou-Yang
    Xu, Xu-Chen
    Lai, Tian -Wen
    Hu, Yue
    Zhou, Hong -Bin
    Chen, Hai -Pin
    Ying, Song -Min
    Li, Wen
    Shen, Hua-Hao
    Chen, Zhi-Hua
    JOURNAL OF IMMUNOLOGY, 2018, 200 (08): : 2571 - 2580
  • [44] Oxidative Stress and Epithelial-Mesenchymal Transition: The Impact of Ubiquitin C-terminal Hydrolase L1 in Cigarette Smoke-Induced COPD
    Yang, Jing Jing
    Liu, Hong Jun
    Wang, Yu Xiu
    Wang, Li Ping
    Gu, Jian Jun
    Gao, Jun Yin
    Ren, Kai Qi
    Min, Ling Feng
    LUNG, 2025, 203 (01)
  • [45] Blocking NOTCH3 Prevents Cigarette Smoke-induced Mucociliary Dysfunction in Airway Epithelial Cells of COPD Donors
    Baumlin, N.
    Kamath, D.
    Yoshida, M.
    Dennis, J. S.
    Miller, S.
    Lafkas, D.
    Kim, M. D.
    Salathe, M. A.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2023, 207
  • [46] Cigarette Smoke-induced Ion Channel and Mucociliary Dysfunction in COPD Airway Epithelial Cells In Vitro: Rescue by Nesolicaftor/Telmisartan
    Silswal, N.
    Baumlin, N.
    Dennis, J.
    Kim, M.
    Salathe, M. A.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2024, 209
  • [47] Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium
    Murray, Lynne A.
    Dunmore, Rebecca
    Camelo, Ana
    Da Silva, Carla A.
    Gustavsson, Malin J.
    Habiel, David M.
    Hackett, Tillie L.
    Hogaboam, Cory M.
    Sleeman, Matthew A.
    Knight, Darryl A.
    RESPIRATORY RESEARCH, 2017, 18
  • [48] Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium
    Lynne A. Murray
    Rebecca Dunmore
    Ana Camelo
    Carla A. Da Silva
    Malin J. Gustavsson
    David M. Habiel
    Tillie L Hackett
    Cory M. Hogaboam
    Matthew A. Sleeman
    Darryl A. Knight
    Respiratory Research, 18
  • [49] Fisetin suppresses cigarette smoke extract-induced epithelial to mesenchymal transition of airway epithelial cells through regulating COX-2/MMPs/13-catenin pathway
    Agraval, Hina
    Sharma, Jiten R.
    Prakash, Nutan
    Yadav, Umesh C. S.
    CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 351
  • [50] Azithromycin ameliorated cigarette smoke-induced airway epithelial barrier dysfunction by activating Nrf2/GCL/GSH signaling pathway
    Yun Song
    Wenhuan Fu
    Youzhi Zhang
    Doudou Huang
    Jian Wu
    Shuangmei Tong
    Mingkang Zhong
    Huifang Cao
    Bin Wang
    Respiratory Research, 24