Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium

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作者
Lynne A. Murray
Rebecca Dunmore
Ana Camelo
Carla A. Da Silva
Malin J. Gustavsson
David M. Habiel
Tillie L Hackett
Cory M. Hogaboam
Matthew A. Sleeman
Darryl A. Knight
机构
[1] MedImmune Ltd,Respiratory, Inflammation and Autoimmunity
[2] AstraZeneca R&D,Respiratory, Inflammation and Autoimmunity innovative Medicines Unit
[3] University of British Columbia,Department of Anesthesiology, Pharmacology and Therapeutics
[4] Cedars-Sinai Medical Center,Department of Medicine
[5] University of British Columbia,James Hogg Research Centre
[6] School of Biomedical Sciences and Pharmacy,Priority Research Centre for Healthy Lungs
[7] University of Newcastle and Hunter Medical Research Institute,undefined
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TGFβ1; Poly I:C; Remodelling; Apoptosis;
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