Gold(I)-Catalyzed Functionalization of Benzhydryl C(sp3)-H Bonds

被引：26
|
作者：
Cera, Gianpiero [1 ]
Chiarucci, Michel [1 ]
Dosi, Federico [1 ]
Bandini, Marco [1 ]
机构：
[1] Alma Mater Studiorum Univ Bologna, Dept Chem G Ciamician, I-40126 Bologna, Italy
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2013年 / 355卷 / 11-12期
关键词：
CH functionalization; gold catalysis; 1; 5-hydride shift; naphthalenes; N-HETEROCYCLIC CARBENES; C-C; HYDROGEN SHIFTS; GOLD CATALYSIS; CYCLOISOMERIZATION; ACTIVATION; HYDROARYLATION; CYCLOADDITION; CYCLIZATIONS; ALLENES;
D O I：
10.1002/adsc.201300525
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The selective activation/functionalization of benzhydryl C(sp(3))-H bonds is documented. The gold complex XPhosAuNTf(2) turned out to be an efficient catalyst (5mol%) to transform readily available propargylic esters into di- or trisubstituted naphthalenes in high yield. A 1,5-hydride shift is postulated as the key step of the cascade reaction sequence.
引用
收藏
页码：2227 / 2231
页数：5
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