A New Rhodamine-Based "Off-On" Fluorescent Chemosensor for Hg (II) Ion and its Application in Imaging Hg (II) in Living Cells

被引：29

作者：

Yan, Fanyong ^{[1
]}

Cao, Donglei ^{[1
]}

Wang, Meng ^{[1
]}

Yang, Ning ^{[1
]}

Yu, Qiuhua ^{[1
]}

Dai, Linfeng ^{[1
]}

Chen, Li ^{[1
]}

机构：

[1] Tianjin Polytech Univ, Key Lab Fiber Modificat & Funct Fiber Tianjin, State Key Lab Hollow Fiber Membrane Mat & Proc, Tianjin 300160, Peoples R China

来源：

JOURNAL OF FLUORESCENCE | 2012年 / 22卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Hg (II) ion; Rhodamine derivative; Fluorescence enhancement; Chemosensor; Fluorescent image; living cells; RECOGNITION PREFERENCE; SELECTIVE DETECTION; MERCURY;

D O I：

10.1007/s10895-012-1065-x

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel rhodamine derivative (Rh-C), synthesized by the reaction of rhodamine ethylenediamine and cinnamoyl chloride, was evaluated as a chemoselective Hg2+ ion sensor. Addition of Hg2+ to an ethanol aqueous solution of the Rh-C resulted in a color change from colorless to obvious pink color together with distinctive changes in UV-vis absorption spectrum and fluorescence spectrum. However, other common alkali-, alkaline earth-, transition- and rare earth metal ions induced no or minimal spectral changes. The interaction of Hg2+ and sensor Rh-C was proven to adopt a 1:1 binding stoichiometry and the recognition process is reversible. The chemosensor displayed a linear response to Hg2+ in the range of 0.4-5 mu M with a detection limit of 7.4 x 10(-8) M. The sensor Rh-C was also successfully applied to the imaging of Hg2+ in HL-7702 cells.

引用

页码：1249 / 1256

页数：8

共 50 条

[41] Al(iii)-responsive "off-on" chemosensor based on rhodamine derivative and its application in cell imaging
Yu, Chunwei
Jian, Li
Ji, Yuxiang
Zhang, Jun
RSC ADVANCES, 2018, 8 (54): : 31106 - 31112
[42] A new FRET ratiometric fluorescent chemosensor for Hg2+ and its application in living EC 109 cells
Song, Jianhua
Huai, Manxiu
Wang, Cuicui
Xu, Zhanhui
Zhao, Yufen
Ye, Yong
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2015, 139 : 549 - 554
[43] A squaraine-based red emission off-on chemosensor for biothiols and its application in living cells imaging
Liu, Xiao-Dong
Sun, Ru
Ge, Jian-Feng
Xu, Yu-Jie
Xu, Ying
Lu, Jian-Mei
ORGANIC & BIOMOLECULAR CHEMISTRY, 2013, 11 (25) : 4258 - 4264
[44] Carbon dots-based fluorescent probe for "off-on" sensing of Hg(II) and I-
He, Jiangling
Zhang, Haoran
Zou, Jinliang
Liu, Yingliang
Zhuang, Jianle
Xiao, Yong
Lei, Bingfu
BIOSENSORS & BIOELECTRONICS, 2016, 79 : 531 - 535
[45] Rhodamine functionalized fluorescent probe based on pyrene and triazole platform for Hg(II) ions and its application to bio-imaging
Andrews, S.G. Jebastin
Silviya, S. Benita Jeba
Jebaraj, J. Winfred
Balakrishnan, Chithiraivel
Journal of Photochemistry and Photobiology A: Chemistry, 2025, 462
[46] Rhodamine-based chemosensor for fluorescence determination of trivalent chromium ion in living cells
Li, Dan
Li, Chun-Yan
Qi, Hong-Rui
Tan, Kai-Yue
Li, Yong-Fei
SENSORS AND ACTUATORS B-CHEMICAL, 2016, 223 : 705 - 712
[47] A novel fluorescent ?OFF-ON? sensing strategy for Hg (II) in water based on functionalized gold nanoparticles
Li, Gufeng
Lu, Mingrong
Li, Shaoqing
Yang, Min
Zhang, Yuanling
Zhang, Yanli
Wang, Hongbin
Yang, Wenrong
CHEMOSPHERE, 2022, 303
[48] A sensitive and selective "turn on" fluorescent chemosensor for Hg(II) ion based on a new pyrene-thymine dyad
Wang, Z
Zhang, DQ
Zhu, DB
ANALYTICA CHIMICA ACTA, 2005, 549 (1-2) : 10 - 13
[49] Correction to: An Application of a Schiff-Base Type Reaction in the Synthesis of a New Rhodamine-Based Hg(II)-Sensing Agent
Fulya Cicekbilek
Bahar Yilmaz
Mevlut Bayrakci
Orhan Gezici
Journal of Fluorescence, 2020, 30 : 221 - 221
[50] Characterization of a Hg2+-Selective Fluorescent Probe Based on Rhodamine B and Its Imaging in Living Cells
Zhang, Wenting
Yu, Chunwei
Yang, Mei
Wen, Shaobai
Zhang, Jun
MOLECULES, 2021, 26 (11):

← 1 2 3 4 5 →