Cellulose-Sulfonic Acid: An Efficient, Recyclable, and Biodegradable Solid Acid Catalyst for the Synthesis of 3-Aminoalkylindoles

被引：5

作者：

Satyanarayana, S. ^{[1
]}

Kumar, K. Praveen ^{[1
]}

Reddy, P. Lakshmi ^{[1
]}

Narender, R. ^{[1
]}

Narasimhulu, G. ^{[1
]}

Reddy, B. V. Subba ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

CHEMISTRY LETTERS | 2013年 / 42卷 / 09期

关键词：

ONE-POT SYNTHESIS; FRIEDEL-CRAFTS ALKYLATION; SOLVENT-FREE CONDITIONS; INDOLE ALKALOIDS; SULFURIC-ACID; 3-COMPONENT SYNTHESIS; SUBSTITUTED INDOLES; PRINS-CYCLIZATION; DERIVATIVES; INHIBITORS;

D O I：

10.1246/cl.130370

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three-component coupling (3CC) of indoles, aldehydes, and N-alkylanilines has been accomplished using a catalytic amount of cellulose-sulfonic acid under mild reaction conditions to furnish the 3-aminoalkylindoles at room temperature in short reaction times and in relatively good to excellent yields and selectivity. The use of biodegradable cellulose-sulfonic acid makes this method quite simple, convenient, and economically viable for the synthesis of 3-aminoalkylindoles.

引用

页码：972 / 974

页数：3

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