Facile Synthesis of Hydrazine Derivatives of 5H-Pyrrolo[3,4-b]pyrazine and 1H-Pyrrolo[3,4-b]quinoxaline

被引：6
|
作者：
Hordiyenko, Olga V. [1 ]
Rudenko, Igor V. [1 ]
Zamkova, Irina A. [1 ]
Denisenko, Oleksandr V. [1 ]
Biitseva, Angelina V. [1 ]
Arrault, Axelle [2 ]
Tolmachev, Andrei A. [1 ]
机构：
[1] Taras Shevchenko Natl Univ Kyiv, UA-01601 Kiev, Ukraine
[2] ENSIC, INPL, Lab Chim Phys Macromol, F-54001 Nancy, France
来源：
SYNTHESIS-STUTTGART | 2013年 / 45卷 / 24期
关键词：
heterocycles; nitriles; cyclization; chemoselectivity; hydrazones; HYDROGEN-CYANIDE CHEMISTRY; EXCITED-STATE; COMPLEXES; DIIMINOSUCCINONITRILE; DIAMINOMALEONITRILE; QUINOXALINES;
D O I：
10.1055/s-0033-1340042
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A convenient and efficient route for the chemoselective synthesis of carbohydrazide, arenesulfonylhydrazide, and thiosemicarbazone derivatives of 5H-pyrrolo[3,4-b]pyrazine and 1H-pyrrolo[3,4-b]quinoxaline from the corresponding dinitriles and substituted hydrazines was elaborated. The synthesis of starting pyrazine-2,3-dicarbonitrile was sufficiently improved by using concentrated HCl as a catalyst.
引用
收藏
页码：3375 / 3382
页数：8
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