Facile Synthesis of Hydrazine Derivatives of 5H-Pyrrolo[3,4-b]pyrazine and 1H-Pyrrolo[3,4-b]quinoxaline

被引：6

作者：

Hordiyenko, Olga V. ^{[1
]}

Rudenko, Igor V. ^{[1
]}

Zamkova, Irina A. ^{[1
]}

Denisenko, Oleksandr V. ^{[1
]}

Biitseva, Angelina V. ^{[1
]}

Arrault, Axelle ^{[2
]}

Tolmachev, Andrei A. ^{[1
]}

机构：

[1] Taras Shevchenko Natl Univ Kyiv, UA-01601 Kiev, Ukraine

[2] ENSIC, INPL, Lab Chim Phys Macromol, F-54001 Nancy, France

来源：

SYNTHESIS-STUTTGART | 2013年 / 45卷 / 24期

关键词：

heterocycles; nitriles; cyclization; chemoselectivity; hydrazones; HYDROGEN-CYANIDE CHEMISTRY; EXCITED-STATE; COMPLEXES; DIIMINOSUCCINONITRILE; DIAMINOMALEONITRILE; QUINOXALINES;

D O I：

10.1055/s-0033-1340042

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient and efficient route for the chemoselective synthesis of carbohydrazide, arenesulfonylhydrazide, and thiosemicarbazone derivatives of 5H-pyrrolo[3,4-b]pyrazine and 1H-pyrrolo[3,4-b]quinoxaline from the corresponding dinitriles and substituted hydrazines was elaborated. The synthesis of starting pyrazine-2,3-dicarbonitrile was sufficiently improved by using concentrated HCl as a catalyst.

引用

页码：3375 / 3382

页数：8

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