Genetic diversity of invasive strains of Haemophilus influenzae type b before and after introduction of the conjugate vaccine in Italy

被引：7

作者：

Cerquetti, Marina

Cardines, Rita

Giufre, Maria

Sofia, Tonino

D'Ambrosio, Fabio

Mastrantonio, Paola

Atti, Marta Luisa Ciofi degli

机构：

[1] Ist Super Sanita, Dept Infect Parasit & Immune Mediated Dis, I-00161 Rome, Italy

[2] Ist Super Sanita, Natl Ctr Epidemiol Surveillance & Hlth Promot, I-00161 Rome, Italy

来源：

CLINICAL INFECTIOUS DISEASES | 2006年 / 43卷 / 03期

关键词：

D O I：

10.1086/505499

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We determined the genotypes of 95 invasive Haemophilus influenzae type b (Hib) strains collected before and after introduction of widespread Hib vaccination in Italy. No substantial change in genetic diversity was highlighted by pulsed-field gel electrophoresis. However, an upward temporal trend in proportion of strains possessing multiple copies of the capsulation b locus was detected (P = .03).

引用

页码：317 / 319

页数：3

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