Genetic diversity of invasive strains of Haemophilus influenzae type b before and after introduction of the conjugate vaccine in Italy

被引：7
|
作者：
Cerquetti, Marina
Cardines, Rita
Giufre, Maria
Sofia, Tonino
D'Ambrosio, Fabio
Mastrantonio, Paola
Atti, Marta Luisa Ciofi degli
机构：
[1] Ist Super Sanita, Dept Infect Parasit & Immune Mediated Dis, I-00161 Rome, Italy
[2] Ist Super Sanita, Natl Ctr Epidemiol Surveillance & Hlth Promot, I-00161 Rome, Italy
来源：
CLINICAL INFECTIOUS DISEASES | 2006年 / 43卷 / 03期
关键词：
D O I：
10.1086/505499
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We determined the genotypes of 95 invasive Haemophilus influenzae type b (Hib) strains collected before and after introduction of widespread Hib vaccination in Italy. No substantial change in genetic diversity was highlighted by pulsed-field gel electrophoresis. However, an upward temporal trend in proportion of strains possessing multiple copies of the capsulation b locus was detected (P = .03).
引用
收藏
页码：317 / 319
页数：3
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