Austdiol, fulvic acid and citromycetin derivatives from an endolichenic fungus, Myxotrichum sp.

被引：26
|
作者：
Yuan, Chao [1 ,2 ]
Wang, Hai-Ying [4 ]
Wu, Chang-Sheng [3 ]
Jiao, Yang [3 ]
Li, Ming [4 ]
Wang, Yan-Yan [3 ]
Wang, Shu-Qi [3 ]
Zhao, Zun-Tian [4 ]
Lou, Hong-Xiang [3 ]
机构：
[1] Chinese Acad Med Sci, Inst Med Plant Dev Yunnan Branch, Jinghong 666100, Peoples R China
[2] Peking Union Med Coll, Jinghong 666100, Peoples R China
[3] Shandong Univ, Dept Nat Prod Chem, Key Lab Chem Biol, Minist Educ,Sch Pharmaceut Sci, Jinan 250012, Peoples R China
[4] Shandong Normal Univ, Coll Life Sci, Jinan 250014, Peoples R China
来源：
PHYTOCHEMISTRY LETTERS | 2013年 / 6卷 / 04期
基金：
中国国家自然科学基金;
关键词：
Endolichenic fungus; Metabolites; Antigungal activity; Cytotoxicity; DIKETOPIPERAZINES; HEPTAKETIDES; METABOLITES;
D O I：
10.1016/j.phytol.2013.08.011
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A new austdiol analog myxodiol A (1), three novel fulvic acid derivatives myxotrichin A-C (2-4), and a new citromycetin analog myxotrichin D (5), were isolated from an endolichenic fungus Myxotrichum sp. inhabiting the lichen Cetraria islandica (L.) Ach. The structures of these compounds were elucidated unequivocally on the basis of comprehensive analysis of MS and NMR data. Compounds 2 and 5 displayed very weak cytotoxicity against human leukemia cell line K562, and compounds 1 showed very weak antifungal activity against Candida albicans (sc5314). (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：662 / 666
页数：5
相关论文
共 50 条
  • [21] Polyketide-Terpene Hybrid Metabolites from an Endolichenic Fungus Pestalotiopsis sp.
    Yuan, Chao
    Ding, Gang
    Wang, Hai-Ying
    Guo, Yu-Hua
    Shang, Hai
    Ma, Xiao-Jun
    Zou, Zhong-Mei
    BIOMED RESEARCH INTERNATIONAL, 2017, 2017
  • [22] Phaeosphaerins A-F, Cytotoxic Perylenequinones from an Endolichenic Fungus, Phaeosphaeria sp.
    Li, Gang
    Wang, Haiying
    Zhu, Rongxiu
    Sun, Lingmei
    Wang, Lining
    Li, Ming
    Li, Yaoyao
    Liu, Yongqing
    Zhao, Zuntian
    Lou, Hongxiang
    JOURNAL OF NATURAL PRODUCTS, 2012, 75 (02): : 142 - 147
  • [23] DERIVATIVES OF HYDROXYQUINOL .3. STRUCTURE OF FULVIC ACID - SYNTHESES AND REACTIONS OF DEGRADATION PRODUCTS OF FULVIC ACID AND OF CITROMYCETIN
    DEAN, FM
    RANDELL, DR
    JOURNAL OF THE CHEMICAL SOCIETY, 1961, (MAR): : 798 - &
  • [24] Short Lecture "Chemical and biocidal characterization of metabolites from endolichenic fungus Xylaria sp."
    Lyssaios, F. A.
    Gonzalez-Coloma, A. A.
    Andres Yeves, M. F.
    Diaz Hernandez, C. E.
    PLANTA MEDICA, 2022, 88 (15) : 1416 - 1417
  • [25] New diketopiperazine dimers and 4-hydroxyphenylacetates from an endolichenic fungus Aspergillus sp.
    Su, Bingjie
    Zhang, Tao
    Mao, Mengjia
    Wang, Renzhong
    You, Baoqing
    Zhang, Jing
    Yu, Liyan
    Si, Shuyi
    Wu, Jingshuai
    Chen, Minghua
    FITOTERAPIA, 2025, 180
  • [26] Bioactive α-Pyrone Derivatives from the Endolichenic Fungus Dothideomycetes sp EL003334
    Kim, Gil Soo
    Ko, Wonmin
    Kim, Jong Won
    Jeong, Min-Hye
    Ko, Sung-Kyun
    Hur, Jae-Seoun
    Oh, Hyuncheol
    Jang, Jae-Hyuk
    Ahn, Jong Seog
    JOURNAL OF NATURAL PRODUCTS, 2018, 81 (04): : 1084 - 1088
  • [27] Biopesticide Compounds from an Endolichenic Fungus Xylaria sp. Isolated from the Lichen Hypogymnia tubulosa
    Lyssaios, Fotios A.
    Gonzalez-Coloma, Azucena
    Fe Andres, Maria
    Diaz, Carmen E.
    MOLECULES, 2025, 30 (03):
  • [28] Dlhawksworthia flavoparmeliae sp. nov., a new endolichenic fungus in Phaeosphaeriaceae
    Si, Hong-Li
    Zheng, Xiao-Xiao
    Lin, Xin-Chao
    Su, Yue-Min
    Bose, Tanay
    Chang, Run-Lei
    PHYTOTAXA, 2021, 525 (01) : 51 - 58
  • [29] Two new naphthalene derivatives from an endolichenic fungal strain Scopulariopsis sp.
    Yang, Fan
    Chen, Guo-Dong
    Gao, Hao
    Li, Xiao-Xia
    Wu, Yang
    Guo, Liang-Dong
    Yao, Xin-Sheng
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2012, 14 (11) : 1059 - 1063
  • [30] Two new usnic acid derivatives from the endophytic fungus Mycosphaerella sp.
    de Oliveira, Djalma M.
    Pereira, Cristiane B.
    Mendes, Graziele
    Junker, Jochen
    Kolloff, Markus
    Rosa, Luiz H.
    Rosa, Carlos A.
    Alves, Tania M. A.
    Zani, Carlos L.
    Johann, Susana
    Cota, Betania B.
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES, 2018, 73 (11-12): : 449 - 455
12345