Isolation of xestosterol esters of brominated acetylenic fatty acids from the marine sponge Xestospongia testudinaria

被引:28
|
作者
Pham, NB
Butler, MS
Hooper, JNA
Moni, RW
Quinn, RJ [1 ]
机构
[1] Griffith Univ, Queensland Pharmaceut Res Inst, Brisbane, Qld 4111, Australia
[2] Queensland Museum, Brisbane, Qld 4101, Australia
来源
JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 10期
关键词
D O I
10.1021/np9901635
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The CH2Cl2 extract of the marine sponge Xestospongia testudinaria inhibited [H-3]DPCPX binding to rat-brain adenosine Al receptors. Bioassay-guided fractionation led to the isolation of a known brominated acetylenic fatty acid 1 as the active component. Also isolated were two novel sterol esters 2 and 3. All structures were determined on the basis of their spectroscopic data.
引用
收藏
页码:1439 / 1442
页数:4
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