Epiregulin and Amphiregulin expression defines a subset of colorectal tumors sensitive to EGFR inhibition

被引：0
|
作者：
Jacobs, Bart
Biesmans, Bart
De Roock, Wendy
De Schutter, Jef
Van Cutsem, Eric
Tejpar, Sabine
机构：
[1] Katholieke Univ Leuven, Ctr Human Genet, Leuven, Belgium
[2] Univ Hosp Gasthuisberg, Digest Oncol Unit, Leuven, Belgium
来源：
CANCER RESEARCH | 2009年 / 69卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1346
引用
收藏
页数：1
相关论文
共 50 条
  • [21] Combined epiregulin (EREG) and amphiregulin (AREG) expression levels as a biomarker of prognosis and panitumumab benefit in RAS-wt advanced colorectal cancer (aCRC).
    Seligmann, Jenny F.
    Elliott, Faye
    Richman, Susan
    Jacobs, Bart
    Hemmings, Gemma
    Barrett, Jenny
    Tejpar, Sabine
    Quirke, Philip
    Seymour, Matthew T.
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [22] HDAC Inhibition Decreases the Expression of EGFR in Colorectal Cancer Cells
    Chou, Chia-Wei
    Wu, Ming-Shiang
    Huang, Wei-Chien
    Chen, Ching-Chow
    PLOS ONE, 2011, 6 (03):
  • [23] EGFR status and expression of downstream kinases in colorectal tumors and metastatic sites
    Nature Clinical Practice Oncology, 2007, 4 : 616 - 616
  • [24] EGFR status and expression of downstream kinases in colorectal tumors and metastatic sites
    不详
    NATURE CLINICAL PRACTICE ONCOLOGY, 2007, 4 (11): : 616 - 616
  • [25] EGFR expression variance in paired colorectal cancer primary and metastatic tumors
    Yarom, Nirit
    Marginean, Celia
    Moyana, Terence
    Gorn-Hondermann, Ivan
    Birnboim, H. Chaim
    Marginean, Horia
    Auer, Rebecca C.
    Vickers, Michael
    Asmis, Timothy R.
    Maroun, Jean
    Jonker, Derek
    CANCER BIOLOGY & THERAPY, 2010, 10 (05) : 416 - 421
  • [26] Tn Antigen Expression Defines an Immune Cold Subset of Mismatch-Repair Deficient Colorectal Cancer
    Matsumoto, Takuro
    Okayama, Hirokazu
    Nakajima, Shotaro
    Saito, Katsuharu
    Nakano, Hiroshi
    Endo, Eisei
    Kase, Koji
    Ito, Misato
    Yamauchi, Naoto
    Yamada, Leo
    Kanke, Yasuyuki
    Onozawa, Hisashi
    Fujita, Shotaro
    Sakamoto, Wataru
    Saito, Motonobu
    Saze, Zenichiro
    Momma, Tomoyuki
    Mimura, Kosaku
    Kono, Koji
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (23) : 1 - 13
  • [27] CIRCULATING AMPHIREGULIN (AR) PLASMA LEVELS AS SURROGATE PHARMACODYNAMIC MARKERS OF EGFR INHIBITION WITH CETUXIMAB IN METASTATIC COLORECTAL CANCER (MCRC) PATIENTS
    Loupakis, F.
    Cremolini, C.
    Fioravanti, A.
    Lupi, C.
    Ferrarini, I
    Orlandi, P.
    Sensi, E.
    Canu, B.
    Salvatore, L.
    Di Desidero, T.
    Masi, G.
    Fontanini, G.
    Danesi, R.
    Bocci, G.
    Falcone, A.
    ANNALS OF ONCOLOGY, 2010, 21 : 36 - 36
  • [28] Elevated Expression of the Tyrosine Phosphatase SHP-1 Defines a Subset of High-Grade Breast Tumors
    Insabato, Luigi
    Amelio, Ivano
    Quarto, Maria
    Zannetti, Antonella
    Tolino, Fabio
    de Mauro, Gaia
    Cerchia, Laura
    Riccio, Patrizia
    Baumhoer, Daniel
    Condorelli, Gerolama
    Terracciano, Luigi
    de Franciscis, Vittorio
    ONCOLOGY, 2009, 77 (06) : 378 - 384
  • [29] Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer
    Seligmann, Jenny F.
    Elliott, Faye
    Richman, Susan D.
    Jacobs, Bart
    Hemmings, Gemma
    Brown, Sarah
    Barrett, Jennifer H.
    Tejpar, Sabine
    Quirke, Philip
    Seymour, Matthew T.
    JAMA ONCOLOGY, 2016, 2 (05) : 633 - 642
  • [30] Prediction of homologous recombination deficiency identifies colorectal tumors sensitive to PARP inhibition
    Corti, Giorgio
    Buzo, Kristi
    Berrino, Enrico
    Miotto, Martina
    Aquilano, Maria Costanza
    Lentini, Marilena
    Bellomo, Sara Erika
    Lorenzato, Annalisa
    Bartolini, Alice
    Mauri, Gianluca
    Lazzari, Luca
    Russo, Mariangela
    Di Nicolantonio, Federica
    Siena, Salvatore
    Marsoni, Silvia
    Marchio, Caterina
    Bardelli, Alberto
    Arena, Sabrina
    NPJ PRECISION ONCOLOGY, 2024, 8 (01)
12345