Protein expression changes in cells inoculated with Equine Influenza Virus: antibody microarray analysis

被引：0
|
作者：
Rozek, W. [1 ]
Kwasnik, M. [1 ]
Zmudzinski, J. F. [1 ]
机构：
[1] Natl Inst Vet Res, Dept Virol, PL-24100 Pulawy, Poland
来源：
POLISH JOURNAL OF VETERINARY SCIENCES | 2013年 / 16卷 / 04期
关键词：
equine influenza; influenza; horses; antibody microarrays; proteomics; CYTOCHROME-C RELEASE; APOPTOSIS; DEATH; GENE; REPLICATION; ACTIVATION; BCL-X(L); KINASE; BCL-2;
D O I：
10.2478/pjvs-2013-0094
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Changes in the level of cellular proteins in cells inoculated with equine influenza virus H7N7 and H3N8 were studied with microarray technique. H3N8 induced pro-apoptotic proteins while H7N7 induced both pro- as well as anti-apoptotic factors. The higher level of some cytoskeleton components and proteins involved in the protein quality control was recorded. Relatively high number of proteins involved in the regulation of transcription was down-regulated. The pattern of changes observed for H7N7 and H3N8 may reflect differences in the biological properties of both serotypes.
引用
收藏
页码：663 / 669
页数：7
相关论文
共 50 条
  • [31] A RAPID METHOD FOR THE ANALYSIS OF INFLUENZA-VIRUS GENES - APPLICATION TO THE REASSORTMENT OF EQUINE INFLUENZA-VIRUS GENES
    ADEYEFA, CAO
    QUAYLE, K
    MCCAULEY, JW
    VIRUS RESEARCH, 1994, 32 (03) : 391 - 399
  • [32] Expression of neuraminidase of influenza virus in Escherichia coli cells by removing of transmembrane domain of the protein
    Romanik, A.
    Kesik-Brodacka, M.
    Baran, P.
    Florys, K.
    Plucienniczak, G.
    Plucienniczak, A.
    FEBS JOURNAL, 2012, 279 : 339 - 339
  • [33] A prototype antibody microarray platform to monitor changes in protein tyrosine phosphorylation
    Gembitsky, DS
    Lawlor, K
    Jacovina, A
    Yaneva, M
    Tempst, P
    MOLECULAR & CELLULAR PROTEOMICS, 2004, 3 (11) : 1102 - 1118
  • [34] Development of a high density hemagglutinin protein microarray to determine the breadth of influenza antibody responses
    Desbien, Anthony L.
    Van Hoeven, Neal
    Reed, Steven J.
    Casey, Allen C.
    Laurance, John D.
    Baldwin, Susan L.
    Duthie, Malcolm S.
    Reed, Steven G.
    Carter, Darrick
    BIOTECHNIQUES, 2013, 54 (06) : 345 - 348
  • [35] The Influenza NS1 Protein: What Do We Know in Equine Influenza Virus Pathogenesis?
    Barba, Marta
    Daly, Janet M.
    PATHOGENS, 2016, 5 (03)
  • [36] Cultures of equine respiratory epithelial cells and organ explants as tools for the study of equine influenza virus infection
    C. Lin
    R. E. Holland Jr
    N. M. Williams
    T. M. Chambers
    Archives of Virology, 2001, 146 : 2239 - 2247
  • [37] Cultures of equine respiratory epithelial cells and organ explants as tools for the study of equine influenza virus infection
    Lin, C
    Holland, RE
    Williams, NM
    Chambers, TM
    ARCHIVES OF VIROLOGY, 2001, 146 (11) : 2239 - 2247
  • [38] Metabolic machinery encrypted in the Raman spectrum of influenza A virus-inoculated mammalian cells
    Pezzotti, Giuseppe
    Zhu, Wenliang
    Adachi, Tetsuya
    Horiguchi, Satoshi
    Marin, Elia
    Boschetto, Francesco
    Ogitani, Eriko
    Mazda, Osam
    JOURNAL OF CELLULAR PHYSIOLOGY, 2020, 235 (06) : 5146 - 5170
  • [39] Microarray analysis of Streptococcus pneumoniae gene expression changes to human lung epithelial cells
    Song, Xin-Ming
    Connor, Wayne
    Jalal, Shakiba
    Hokamp, Karsten
    Potter, Andrew A.
    CANADIAN JOURNAL OF MICROBIOLOGY, 2008, 54 (03) : 189 - 200
  • [40] EFFECTS OF ANTIBODY TO THE INFLUENZA-A VIRUS M2 PROTEIN ON M2 SURFACE EXPRESSION AND VIRUS ASSEMBLY
    HUGHEY, PG
    ROBERTS, PC
    HOLSINGER, LJ
    ZEBEDEE, SL
    LAMB, RA
    COMPANS, RW
    VIROLOGY, 1995, 212 (02) : 411 - 421
12345