Sulfur dioxide prodrugs: triggered release of SO2 via a click reaction

被引：60
|
作者：
Wang, Wenyi
Ji, Xingyue [1 ]
Du, Zhenming
Wang, Binghe [1 ]
机构：
[1] Georgia State Univ, Dept Chem, Atlanta, GA 30303 USA
来源：
CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 08期
基金：
美国国家卫生研究院;
关键词：
HYDROGEN-SULFIDE; 1,1-DIOXIDE; DERIVATIVES; BISULFITE; CYSTEINE; SYSTEMS; DONORS; PROBES; CELLS; THIOL;
D O I：
10.1039/c6cc08844a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Sulfur dioxide (SO2) is being recognized as a possible endogenous gasotransmitter with importance on par with that of NO, CO, and H2S. Herein we describe a series of SO2 prodrugs that are activated for SO2 release via a bioorthogonal click reaction. The release rate can be tuned by adjusting the substituents on the prodrug.
引用
收藏
页码：1370 / 1373
页数：4
相关论文
共 50 条
  • [21] Sizing of a Catalytic Reactor for Sulfuric Acid Reduction to Sulfur Dioxide Based on the Activation Parameters of SO3→SO2 Reaction
    Balla, Ancuta
    Axente, Damian
    Marcu, Cristina
    REVISTA DE CHIMIE, 2015, 66 (04): : 556 - 561
  • [22] DETECTION OF SULFUR DIOXIDE(SO2) AND DOUBTLESS CS2 IN THE ATMOSPHERE OF VENUS
    HUA, CT
    COURTES, G
    HUUDOAN, N
    COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE B, 1979, 288 (11): : 187 - &
  • [23] SULFUR-DIOXIDE (SO2) EFFECTS SPONTANEOUS WHEEL RUNNING IN HAMSTERS
    SKORNIK, WA
    BRAIN, JD
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1986, 133 (04): : A87 - A87
  • [24] Free, Bound, and Total Sulfur Dioxide (SO2) during Oxidation of Wines
    Sacks, Gavin L.
    Howe, Patricia A.
    Standing, Matthew
    Danilewicz, John C.
    AMERICAN JOURNAL OF ENOLOGY AND VITICULTURE, 2020, 71 (04): : 266 - 277
  • [25] SO2 PROCESSING - ECONOMIC IMPACT OF SULFUR-DIOXIDE POLLUTION CONTROLS
    GAMSE, RN
    SPEYER, J
    CHEMICAL ENGINEERING PROGRESS, 1974, 70 (06) : 45 - 48
  • [26] Biomonitoring of air pollution sulfur dioxide (SO2) by Lichen, Lecanora mularis
    Khani, M. R.
    Pirasteh, S.
    Shahabpoor, C.
    Sanij, Dehghani A.
    RESEARCH JOURNAL OF CHEMISTRY AND ENVIRONMENT, 2011, 15 (02): : 933 - 938
  • [27] Sulfur dioxide (SO2) gas transfer process enhanced by corona discharge
    Wang, Zu Wu
    Zeng, Han Cai
    Guo, Jia
    Zhou, Jing
    Liu, Nin
    JOURNAL OF ELECTROSTATICS, 2007, 65 (08) : 485 - 489
  • [28] Synthesis of Cyclic Sulfite Diesters and their Evaluation as Sulfur Dioxide (SO2) Donors
    Malwal, Satish R.
    Pardeshi, Kundansingh A.
    Chakrapani, Harinath
    CHEMBIOCHEM, 2020, 21 (08) : 1201 - 1205
  • [29] SO2 PROCESSING - DUAL ALKALI PROCESS FOR SULFUR-DIOXIDE REMOVAL
    LAMANTIA, CR
    LUNT, RR
    SHAH, IS
    CHEMICAL ENGINEERING PROGRESS, 1974, 70 (06) : 66 - 67
  • [30] INFRARED SPECTROSCOPIC DETERMINATION OF DIPOLE MOMENT OF SO2 (SULFUR DIOXIDE) MOLECULE
    SECROUN, C
    JOUVE, P
    COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE B, 1970, 270 (25): : 1610 - &
12345