Asymmetric Organocatalytic Synthesis of Spiro-cyclopropaneoxindoles

被引：21

作者：

Noole, Artur ^{[1
]}

Malkov, Andrei V. ^{[2
]}

Kanger, Tonis ^{[1
]}

机构：

[1] Tallinn Univ Technol, Dept Chem, EE-12618 Tallinn, Estonia

[2] Univ Loughborough, Dept Chem, Loughborough LE11 3TU, Leics, England

来源：

SYNTHESIS-STUTTGART | 2013年 / 45卷 / 18期

关键词：

spiro compounds; organocatalysis; oxindoles; 3-chlorooxindoles; asymmetric synthesis; ENANTIOSELECTIVE CYCLOPROPANATION; OXINDOLES; SPIROOXINDOLES; CATALYSIS; CENTERS;

D O I：

10.1055/s-0033-1338505

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Straightforward cascade reactions for the synthesis of spiro-cyclopropaneoxindoles are described. The target compounds are obtained in high yields and in good enantio- and diastereoselectivities via hydrogen bonding or iminium catalysis.

引用

页码：2520 / 2524

页数：5

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