A frameshift mutation in hepatocyte nuclear factor 1β cause diabetes by β cell dysfunction and renal dysfunction by abnormal nephron development

被引:0
|
作者
Hattersley, AT
Bingham, C
Shepard, M
Allen, LI
Berry, P
Bulman, M
Frayling, TM
Ellard, S
机构
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
0140
引用
收藏
页码:A33 / A33
页数:1
相关论文
共 50 条
  • [21] Abnormal splicing of hepatocyte nuclear factor 1 alpha in maturity-onset diabetes of the young
    M. Bulman
    L. Harries
    T. Hansen
    M. Shepherd
    W. Kelly
    A. Hattersley
    S. Ellard
    Diabetologia, 2002, 45 : 1463 - 1467
  • [22] Underexpression of hepatocyte nuclear factor-1 in chromophobe renal cell carcinoma
    Wang, Chung-Chieh
    Mao, Tsui-Lien
    Yang, Wan-Ching
    Jeng, Yung-Ming
    HISTOPATHOLOGY, 2013, 62 (04) : 589 - 594
  • [23] A case of hepatocyte nuclear factor-1 alpha diabetes (the new mutation in mody 3)
    Jesic, M. D.
    Sajic, S.
    Maringa, M.
    Jesic, M. M.
    Micic, D. D.
    DIABETOLOGIA, 2007, 50 : S122 - S123
  • [24] β-cell-targeted expression of a dominant-negative mutant of hepatocyte nuclear factor-1α in mice -: Diabetes model with β-cell dysfunction partially rescued by nonglucose secretagogues
    Winzell, MS
    Pacini, G
    Wollheim, CB
    Ahrén, B
    DIABETES, 2004, 53 : S92 - S96
  • [25] Hepatocyte nuclear factor-1β:: A new kindred with renal cysts and diabetes and gene expression in normal human development
    Kolatsi-Joannou, M
    Bingham, C
    Ellard, S
    Bulman, MP
    Allen, LIS
    Hattersley, AT
    Woolf, AS
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2001, 12 (10): : 2175 - 2180
  • [26] Renal cysts and diabetes syndrome resulting from mutations in hepatocyte nuclear factor-1β
    Bingham, C
    Hattersley, AT
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2004, 19 (11) : 2703 - 2708
  • [27] Hepatocyte Nuclear Factor 1β-Associated Kidney Disease: More than Renal Cysts and Diabetes
    Verhave, Jacobien C.
    Bech, Anneke P.
    Wetzels, Jack F. M.
    Nijenhuis, Tom
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2016, 27 (02): : 345 - 353
  • [28] Mutations in hepatocyte nuclear factor 1β are not a common cause of maturity-onset diabetes of the young in the UK
    Beards, F
    Frayling, T
    Bulman, M
    Horikawa, Y
    Allen, L
    Appleton, M
    Bell, GI
    Ellard, S
    Hattersley, AT
    DIABETES, 1998, 47 (07) : 1152 - 1154
  • [29] Functional Analyses of the Mutation in Hepatocyte Nuclear Factor-1a Promoter Region in Chinese Diabetes Pedigrees
    Fang, Qichen
    Jiang, Shan
    Zhang, Rong
    Wang, Congrong
    Xiang, Kunsan
    Jia, Weiping
    DIABETES, 2010, 59 : A339 - A339
  • [30] Beta-cell targeted expression of a dominant-negative hepatocyte nuclear factor (HNF)-1a in mice:: Diabetes model with beta-cell dysfunction rescued by exogenous palmitate
    Winzell, MS
    Wollheim, CB
    Ahrén, B
    DIABETES, 2004, 53 : A359 - A359