The paradoxical role of IL-17 in atherosclerosis

被引：71

作者：

Gong, Fangchen ^{[1
]}

Liu, Zhengxia ^{[1
]}

Liu, Jingning ^{[1
]}

Zhou, Ping ^{[1
]}

Liu, Ying ^{[1
]}

Lu, Xiang ^{[1
]}

机构：

[1] Nanjing Med Univ, Dept Geriatr, Affiliated Hosp 2, Nanjing 210029, Jiangsu, Peoples R China

来源：

CELLULAR IMMUNOLOGY | 2015年 / 297卷 / 01期

基金：

美国国家科学基金会;

关键词：

Atherosclerosis; IL-17; Coronary artery disease; Immunity; DELTA-T-CELLS; ROR-GAMMA-T; SMOOTH-MUSCLE-CELLS; C-REACTIVE PROTEIN; NF-KAPPA-B; MONOCLONAL-ANTIBODY; IMMUNE-RESPONSES; TH17; CELLS; TNF-ALPHA; DIFFERENTIATION;

D O I：

10.1016/j.cellimm.2015.05.007

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Atherosclerosis is a chronic inflammatory disease mediated by innate and adaptive immune responses. In recent years, CD4(+) T cells (Th1, Th2, Treg, and Th17) have been increasingly studied for their role in atherosclerosis pathophysiology, atheroma stability, plaque rupture, and life-threatening acute coronary syndrome. IL-17, a marker cytokine of Th17 cells, has been reported to be involved in the pathogenesis of rheumatoid arthritis, inflammatory bowel disease, and asthma. However, its role in atherosclerosis has been poorly characterized. This article provides a comprehensive overview of the role of IL-17 in the development of atherosclerosis and human coronary artery diseases. (C) 2015 Published by Elsevier Inc.

引用

页码：33 / 39

页数：7

共 50 条

[21] The Role of IL-17 in the Pathogenesis of Psoriasis and Update on IL-17 Inhibitors for the Treatment of Plaque Psoriasis
AbuHilal, Mohn'd
Walsh, Scott
Shear, Neil
JOURNAL OF CUTANEOUS MEDICINE AND SURGERY, 2016, 20 (06) : 509 - 516
[22] Paradoxical skin lesions induced by IL-17 inhibitors in SAPHO syndrome
Li, Yuan
Meng, Fanzhang
Jiang, Haixu
Peng, Qiuwei
Fu, Jingyuan
Yin, Dan
Hou, Xiujuan
Li, Chen
JOURNAL OF DERMATOLOGICAL TREATMENT, 2024, 35 (01)
[23] IL-17 and Th17 Cells in Atherosclerosis Subtle and Contextual Roles
Taleb, Soraya
Tedgui, Alain
Mallat, Ziad
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2015, 35 (02) : 258 - 264
[24] Evidence for a role of IL-17 in alloimmunity: A novel IL-17 antagonist promotes heart graft survival
Antonysamy, MA
Fanslow, WC
Fu, F
Li, W
Qian, S
Troutt, AB
Thomson, AW
TRANSPLANTATION PROCEEDINGS, 1999, 31 (1-2) : 93 - 93
[25] An unexpected role for IL-17 in lymphoid organogenesis
Cupedo, Tom
NATURE IMMUNOLOGY, 2011, 12 (07) : 590 - 592
[26] Role of IL-17 in allergic airway inflammation
Nakae, Susumu
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2008, 128 : 35 - 35
[27] Role of IL-17 in Psoriasis and Psoriatic Arthritis
Raychaudhuri, Siba P.
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2013, 44 (02) : 183 - 193
[28] PATHOGENESIS OF AS, THE ROLE OF THE IL-17/23 AXIS
Bowness, Paul
RHEUMATOLOGY, 2017, 56 : 2 - 3
[29] ROLE OF IL-17 IN THE PATHOMECHANISM OF RENAL FIBROSIS
Himer, Leonora
Himer, Leonora
Szebeni, Beata
Sziksz, Erna
Saijo, Shinobu
Kis, Eva
Prokai, Agnes
Banki, Nora F.
Fekete, Andrea
Tulassay, Tivadar
Vannay, Adam
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2012, 27 : 439 - 440
[30] Is there a role for IL-17 in the pathogenesis of systemic sclerosis?
Chizzolini, Carlo
Dufour, Aleksandra Maria
Brembilla, Nicole Costantino
IMMUNOLOGY LETTERS, 2018, 195 : 61 - 67

← 1 2 3 4 5 →