Comparative Study in Different Filters for Efficient Sterile Filtration

被引：1

作者：

An, Hyun Ho ^{[1
]}

Moon, Byung Seok ^{[2
]}

Park, Hyun Sik ^{[1
]}

Lee, Hong Jin ^{[1
]}

Lee, Sang Ju ^{[3
]}

Oh, Seung Jun ^{[3
]}

Kim, Bom Sahn ^{[2
]}

Lee, Byung Chul ^{[1
,4
]}

Lee, Won Woo ^{[1
]}

Kim, Sang Eun ^{[1
,4
,5
]}

机构：

[1] Seoul Natl Univ, Coll Med, Dept Nucl Med, Bundang Hosp, Seongnam 13620, South Korea

[2] Ewha Womans Univ, Seoul Hosp, Dept Nucl Med, Coll Med, Seoul 07804, South Korea

[3] Univ Ulsan, Asan Med Ctr, Dept Nucl Med, Coll Med, Seoul 05505, South Korea

[4] Adv Inst Convergence Technol, Ctr Nanomol Imaging & Innovat Drug Dev, Suwon 16229, South Korea

[5] Seoul Natl Univ, Grad Sch Convergence Sci & Technol, Dept Transdisciplinary Studies, Seoul 08826, South Korea

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2020年 / 41卷 / 08期

关键词：

Sterile membrane filtration; C-11-Pittsburgh compound B; Radiopharmaceuticals; Positron emission tomography; ALZHEIMERS-DISEASE;

D O I：

10.1002/bkcs.12073

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Simple membrane filtration is suitable as a terminal sterilization method for radiopharmaceuticals due to their short half-life and radiation exposure of process operator. However, it often adheres to the filter membrane and causes a considerable loss of radioactivity. We herein describe the investigation of sterile filtration performance varying individual sterile filters in order to identify the optimal sterile filter on demand for lipophilic radiopharmaceuticals.

引用

页码：824 / 828

页数：5

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