Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK-1092 in Healthy Subjects (HS)

被引：1
|
作者：
Morrow, Linda
Grimm, Michael
Beysen, Carine
Walford, Geoffrey
Duncan, Kelly
Mitra, Pranab K.
Vaddady, Pavan
Hompesch, Marcus
机构：
来源：
DIABETES | 2020年 / 69卷
关键词：
D O I：
10.2337/db20-107-LB
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
107-LB
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Pharmacokinetics, Pharmacodynamics, and Safety of Single-Dose Canagliflozin in Healthy Chinese Subjects
    Chen, Xia
    Hu, Pei
    Vaccaro, Nicole
    Polidori, David
    Curtin, Christopher R.
    Stieltjes, Hans
    Sha, Sue
    Weiner, Sveta
    Devineni, Damayanthi
    [J]. CLINICAL THERAPEUTICS, 2015, 37 (07) : 1483 - 1492
  • [42] Evaluation of the Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose of Emicizumab in Healthy Chinese Subjects
    Li, Haiyan
    Zhang, Weijiang
    Petry, Claire
    Li, Lindong
    Fernandez, Elena
    Kiialainen, Anna
    Feng, Sheng
    Hsu, Wanling
    Li, Li
    Wei, Yudong
    Schmitt, Christophe
    [J]. CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2021, 10 (01): : 30 - 38
  • [43] A randomized, controlled single, and multiple ascending dose trial of the safety, pharmacokinetics and pharmacodynamics of SN1011 in healthy subjects
    Zhu, Leilei
    Shi, Rong
    Zhao, Tongfang
    Ye, Yujie
    Tang, Jie
    Hu, Yihui
    Peng, Peng
    Wang, Dong
    Chong, Clement
    Xu, Guolin
    Leung, Shui-on
    Yuan, Wei'an
    [J]. CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2023, 16 (10): : 1982 - 1996
  • [44] The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP3652 in First-in-Human and Ascending Multiple Oral Dose Studies in Healthy Subjects
    Masaomi Takizawa
    Dirk Cerneus
    Ingrid Michon
    Sanne Rijnders
    Desiree van der Heide
    John Meijer
    Matthias Stoelzel
    Yuichiro Sato
    [J]. Advances in Therapy, 2020, 37 : 3878 - 3900
  • [45] The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP3652 in First-in-Human and Ascending Multiple Oral Dose Studies in Healthy Subjects
    Takizawa, Masaomi
    Cerneus, Dirk
    Michon, Ingrid
    Rijnders, Sanne
    van der Heide, Desiree
    Meijer, John
    Stoelzel, Matthias
    Sato, Yuichiro
    [J]. ADVANCES IN THERAPY, 2020, 37 (09) : 3878 - 3900
  • [46] Safety, tolerance and pharmacokinetics of biolimus A9 in healthy subjects in a single ascending dose study
    Christians, U.
    Dingmann, C.
    Bucher-Bartelson, B.
    Steudel, W.
    [J]. EUROPEAN HEART JOURNAL, 2007, 28 : 216 - 216
  • [47] Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteers
    Butler, Kathleen
    Teng, Renli
    [J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2010, 70 (01) : 65 - 77
  • [48] A PHASE 1, SINGLE AND MULTIPLE ASCENDING DOSE STUDY OF SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF AG-519, AN ALLOSTERIC ACTIVATOR OF PYRUVATE KINASE-R IN HEALTHY SUBJECTS
    Barbier, A.
    Cutie, J.
    Connor, G.
    Merica, E.
    Kung, C.
    Le, K.
    Yang, H.
    Kosinski, P. A.
    Silverman, L.
    Yuan, Z. J.
    Agresta, S.
    Cohen, M.
    [J]. HAEMATOLOGICA, 2016, 101 : 301 - 301
  • [49] A phase I ascending single-dose study of the safety, tolerability, and pharmacokinetics of bosutinib (SKI-606) in healthy adult subjects
    Abbas, Richat
    Hug, Bruce A.
    Leister, Cathie
    El Gaaloul, Myriam
    Chalon, Stephan
    Sonnichsen, Daryl
    [J]. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2012, 69 (01) : 221 - 227
  • [50] Ascending single-dose study of the safety, tolerability, and pharmacokinetics of bosutinib administered orally with multiple doses of ketoconazole to healthy adult subjects
    El Gaaloul, M.
    Abbas, R.
    Hug, B.
    Leister, C.
    Chalon, S.
    Sonnichsen, D.
    [J]. EJC SUPPLEMENTS, 2009, 7 (02): : 132 - 132
12345