Target Ablation of PTH/PTHrP Receptor (PPR) in Osteocytes Induces Hypocalcemia and Impairs Bone Structure

被引:0
|
作者
Divieti, P. P. [1 ]
Powell, W. F. [1 ]
Kobayashi, T. [1 ]
Harris, S. [2 ]
Bringhurst, F. [1 ]
机构
[1] Harvard Univ, Sch Med, Mass Gen Hosp, Endocrine Unit, Boston, MA USA
[2] Univ Texas Hlth Sci Ctr San Antonio, Dept Periodont, San Antonio, TX 78229 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:S45 / S45
页数:1
相关论文
共 50 条
  • [21] The C-terminal domain of PTHrP limits PTH receptor-mediated changes in gene expression in osteocytes
    Sun, Yao
    Ho, Patricia W. M.
    Johnson, Rachelle W.
    Martin, T. John
    Sims, Natalie A.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2018, 33 : 293 - 293
  • [22] Physiological and Pharmacological Roles of PTH and PTHrP in Bone Using Their Shared Receptor, PTH1R
    Martin, T. John
    Sims, Natalie A.
    Seeman, Ego
    ENDOCRINE REVIEWS, 2021, 42 (04) : 383 - 406
  • [23] The PTH/PTHrP receptor modulates the pool of bone marrow stromal cells: Implications for the anabolic action of PTH
    Ohishi, M.
    Purton, L. E.
    Stanford, W. L.
    Scadden, D. T.
    Kronenberg, H. M.
    Schipani, E.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2007, 22 : S396 - S396
  • [24] PTH Receptor Signaling in Osteocytes Governs Periosteal Bone Formation and Intracortical Remodeling
    Rhee, Yumie
    Allen, Matthew R.
    Condon, Keith
    Lezcano, Virginia
    Ronda, Ana C.
    Galli, Carlo
    Olivos, Naomi
    Passeri, Giovanni
    O'Brien, Charles A.
    Bivi, Nicoletta
    Plotkin, Lilian I.
    Bellido, Teresita
    JOURNAL OF BONE AND MINERAL RESEARCH, 2011, 26 (05) : 1035 - 1046
  • [25] Loss of PTH/PTHrP receptor signaling in osteoblasts increases bone mass.
    Kobayashi, T
    Chung, U
    Katagiri, T
    Goad, D
    Lanske, B
    Kronenberg, HM
    JOURNAL OF BONE AND MINERAL RESEARCH, 2000, 15 : S150 - S150
  • [26] TISSUE-SPECIFIC TRANSCRIPTION-START SITE AND 5' ALTERNATIVE SPLICING OF THE PTH/PTHRP RECEPTOR (PPR) GENE
    JOUN, H
    LANSKE, B
    ABOUSAMRA, AB
    JOURNAL OF BONE AND MINERAL RESEARCH, 1995, 10 : S488 - S488
  • [27] Resorption Controls Bone Anabolism Driven by Parathyroid Hormone (PTH) Receptor Signaling in Osteocytes
    Rhee, Yumie
    Lee, Eun-Young
    Lezcano, Virginia
    Ronda, Ana C.
    Condon, Keith W.
    Allen, Matthew R.
    Plotkin, Lilian I.
    Bellido, Teresita
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (41) : 29809 - 29820
  • [28] PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth
    Lanske, B
    Karaplis, AC
    Lee, K
    Luz, A
    Vortkamp, A
    Pirro, A
    Karperien, M
    Defize, LHK
    Ho, C
    Mulligan, RC
    AbouSamra, AB
    Juppner, H
    Segre, GV
    Kronenberg, HM
    SCIENCE, 1996, 273 (5275) : 663 - 666
  • [29] Phospholipase C signaling via the PTH/PTHrP receptor is essential for normal full response to PTH in both bone and kidney
    Guo, J.
    Liu, M.
    Thomas, C. C.
    Yang, D.
    Bouxsein, M. L.
    Schipani, E.
    Bringhurst, F. R.
    Kronenberg, H. M.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2007, 22 : S35 - S35
  • [30] Specific immunolocalization of the human PTH/PTHrP receptor in classical human target tissues and ovary.
    Bruns, ME
    Scott, M
    Ladenson, J
    Iezzoni, J
    Adams, AE
    Suva, LJ
    Ferguson, JE
    Seaner, RM
    Bruns, DE
    JOURNAL OF BONE AND MINERAL RESEARCH, 1997, 12 : S370 - S370