Target Ablation of PTH/PTHrP Receptor (PPR) in Osteocytes Induces Hypocalcemia and Impairs Bone Structure

被引：0
|
作者：
Divieti, P. P. [1 ]
Powell, W. F. [1 ]
Kobayashi, T. [1 ]
Harris, S. [2 ]
Bringhurst, F. [1 ]
机构：
[1] Harvard Univ, Sch Med, Mass Gen Hosp, Endocrine Unit, Boston, MA USA
[2] Univ Texas Hlth Sci Ctr San Antonio, Dept Periodont, San Antonio, TX 78229 USA
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2008年 / 23卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：S45 / S45
页数：1
相关论文
共 50 条
  • [1] Target ablation of PTH/PTHrP receptor in osteocytes
    Divieti, P. P.
    Powell, W. F.
    Kobayashi, T.
    Harris, S. E.
    Bringhurst, F.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2007, 22 : S14 - S14
  • [2] Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses
    Powell, William F., Jr.
    Barry, Kevin J.
    Tulum, Irena
    Kobayashi, Tatsuya
    Harris, Stephen E.
    Bringhurst, F. Richard
    Pajevic, Paola Divieti
    JOURNAL OF ENDOCRINOLOGY, 2011, 209 (01) : 21 - 32
  • [3] Constitutively active PTH/PTHrP receptor (PPR) in bone stromal cells.
    Ohishi, M.
    Purton, L. E.
    Gunes, Y.
    Marzia, M.
    Scadden, D. T.
    Kronenberg, H. M.
    Schipani, E.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2006, 21 : S198 - S198
  • [4] PTH/PTHRP RECEPTOR EXPRESSION ON OSTEOBLASTS AND OSTEOCYTES BUT NOT RESORBING BONE SURFACES IN GROWING RATS
    FERMOR, B
    SKERRY, TM
    JOURNAL OF BONE AND MINERAL RESEARCH, 1995, 10 (12) : 1935 - 1943
  • [5] Ablation of the PTHrP gene or the PTH/PTHrP receptor gene leads to distinct abnormalities in bone development
    Lanske, B
    Amling, M
    Neff, L
    Guiducci, J
    Baron, R
    Kronenberg, HM
    JOURNAL OF CLINICAL INVESTIGATION, 1999, 104 (04): : 399 - 407
  • [6] PTH/PTHrP Receptor (PPR) Signaling in Osteocytes Delays Osteocyte Senescence and Protects from Age-related Osteopenia.
    Saini, Vaibhav
    Fulzele, Keertik
    Liu, Xiaolong
    Dedic, Christopher G.
    Zoubine, Vladimir
    Spatz, Jordan
    Saito, Hiroaki
    Jahn, Katharina
    Khaled, Saman F.
    Held, Kathryn D.
    Hesse, Eric
    Pajevic, Paola Divieti
    JOURNAL OF BONE AND MINERAL RESEARCH, 2014, 29 : S347 - S347
  • [7] Role of PTH/PTHrP Receptor Signaling in Osteocytes in Ovariectomy-Induced Osteopenia
    Garr, Jenna
    Marengi, Dean
    Saini, Vaibhav
    Liu, Xiaolong
    Pajevic, Paola Divieti
    JOURNAL OF BONE AND MINERAL RESEARCH, 2013, 28
  • [8] Calcium fluxes at the bone/plasma interface: Acute effects of parathyroid hormone (PTH) and targeted deletion of PTH/PTH-related peptide (PTHrP) receptor in the osteocytes
    Dedic, Christopher
    Hung, Tin Shing
    Shipley, Alan M.
    Maeda, Akira
    Gardella, Thomas
    Miller, Andrew L.
    Divieti Pajevic, Paola
    Kunkel, Joseph G.
    Rubinacci, Alessandro
    BONE, 2018, 116 : 135 - 143
  • [9] Bone Is a Major Target of PTH/PTHrP Receptor Signaling in Regulation of Fetal Blood Calcium Homeostasis
    Hirai, Takao
    Kobayashi, Tatsuya
    Nishimori, Shigeki
    Karaplis, Andrew C.
    Goltzman, David
    Kronenberg, Henry M.
    ENDOCRINOLOGY, 2015, 156 (08) : 2774 - 2780
  • [10] Constitutively active PTH/PTHrP receptor specifically expressed in osteoblasts enhances bone formation induced by bone marrow ablation
    Ono, Noriaki
    Nakashima, Kazuhisa
    Schipani, Ernestina
    Hayata, Tadayoshi
    Ezura, Yoichi
    Soma, Kunimichi
    Kronenberg, Henry M.
    Noda, Masaki
    JOURNAL OF CELLULAR PHYSIOLOGY, 2012, 227 (02) : 408 - 415
12345