Conformational signatures of 13C chemical shifts in RNA ribose

被引:19
|
作者
Ohlenschlaeger, Oliver [1 ]
Haumann, Sebastian [1 ]
Ramachandran, Ramadurai [1 ]
Goerlach, Matthias [1 ]
机构
[1] Fritz Lipmann Inst, Leibniz Inst Age Res, Biomol NMR Spect, D-07745 Jena, Germany
关键词
NMR spectroscopy; RNA; chemical shift; Ribose; sugar pucker;
D O I
10.1007/s10858-008-9271-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The conformational dependence of (13)C chemical shift values of RNA riboses determined by liquid-state NMR spectroscopy was evaluated using data deposited for RNA structures in the RCSD and BMRB data bases. Results derived support the applicability of the canonical coordinates approach of Rossi and Harbison (J Magn Reson 151:1-8, 2001) in liquid-state NMR to assess the sugar pucker of ribose units in RNA.
引用
收藏
页码:139 / 142
页数:4
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